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Low reliability of DNA methylation across Illumina Infinium platforms in cord blood: implications for replication studies and meta-analyses of prenatal exposures

BACKGROUND: There is an increasing interest in the role of epigenetics in epidemiology, but the emerging research field faces several critical biological and technical challenges. In particular, recent studies have shown poor correlation of measured DNA methylation (DNAm) levels within and across Il...

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Detalles Bibliográficos
Autores principales: Olstad, Emilie Willoch, Nordeng, Hedvig Marie Egeland, Sandve, Geir Kjetil, Lyle, Robert, Gervin, Kristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9238140/
https://www.ncbi.nlm.nih.gov/pubmed/35765087
http://dx.doi.org/10.1186/s13148-022-01299-3