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IL‐1Ra deficiency accelerates intervertebral disc degeneration in C57BL6J mice

The expression of Interleukin‐1ß (IL‐1ß) and its antagonist and Interleukin‐1 receptor antagonist (IL‐1Ra) are correlated with greater human intervertebral disc (IVD) degeneration, suggesting that elevated IL‐1β activity promotes disc degeneration. Many in vitro studies support such a mechanistic re...

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Detalles Bibliográficos
Autores principales:	Swamy, Ganesh, Salo, Paul, Duncan, Neil, Jirik, Frank, Matyas, John
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Inc. 2022
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9238285/ https://www.ncbi.nlm.nih.gov/pubmed/35783913 http://dx.doi.org/10.1002/jsp2.1201

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