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A rare case of small bowel adenocarcinoma complicating coeliac disease

Small bowel adenocarcinoma is an uncommon surgical pathology. Due to non-specific symptoms, most cases present late and pose a challenge to diagnose. We present a case of a small bowel adenocarcinoma in a patient with coeliac disease. A female patient presented to the emergency department with a 3-w...

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Autores principales: Mirza, Muhammad H, Nzewi, Emeka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9238299/
https://www.ncbi.nlm.nih.gov/pubmed/35774478
http://dx.doi.org/10.1093/jscr/rjac300
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author Mirza, Muhammad H
Nzewi, Emeka
author_facet Mirza, Muhammad H
Nzewi, Emeka
author_sort Mirza, Muhammad H
collection PubMed
description Small bowel adenocarcinoma is an uncommon surgical pathology. Due to non-specific symptoms, most cases present late and pose a challenge to diagnose. We present a case of a small bowel adenocarcinoma in a patient with coeliac disease. A female patient presented to the emergency department with a 3-week history of nausea, anorexia and intermittent bilious vomiting. It was associated with crampy abdominal pain. She was diagnosed with coeliac disease two years ago and commenced on a gluten-free diet. A subsequent computed tomography scan of abdomen and pelvis demonstrated a small bowel stricture with dilated proximal and collapsed distal bowel loops. The stricture was surgically resected followed by primary anastomosis. Histology confirmed adenocarcinoma with nodal metastasis. She received adjuvant chemotherapy and recovered well. In general, small bowel adenocarcinomas are rare and a high index of suspicion is required in patients with predisposing factors e.g. coeliac disease.
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spelling pubmed-92382992022-06-29 A rare case of small bowel adenocarcinoma complicating coeliac disease Mirza, Muhammad H Nzewi, Emeka J Surg Case Rep Case Report Small bowel adenocarcinoma is an uncommon surgical pathology. Due to non-specific symptoms, most cases present late and pose a challenge to diagnose. We present a case of a small bowel adenocarcinoma in a patient with coeliac disease. A female patient presented to the emergency department with a 3-week history of nausea, anorexia and intermittent bilious vomiting. It was associated with crampy abdominal pain. She was diagnosed with coeliac disease two years ago and commenced on a gluten-free diet. A subsequent computed tomography scan of abdomen and pelvis demonstrated a small bowel stricture with dilated proximal and collapsed distal bowel loops. The stricture was surgically resected followed by primary anastomosis. Histology confirmed adenocarcinoma with nodal metastasis. She received adjuvant chemotherapy and recovered well. In general, small bowel adenocarcinomas are rare and a high index of suspicion is required in patients with predisposing factors e.g. coeliac disease. Oxford University Press 2022-06-28 /pmc/articles/PMC9238299/ /pubmed/35774478 http://dx.doi.org/10.1093/jscr/rjac300 Text en Published by Oxford University Press and JSCR Publishing Ltd. All rights reserved. © The Author(s) 2022. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Case Report
Mirza, Muhammad H
Nzewi, Emeka
A rare case of small bowel adenocarcinoma complicating coeliac disease
title A rare case of small bowel adenocarcinoma complicating coeliac disease
title_full A rare case of small bowel adenocarcinoma complicating coeliac disease
title_fullStr A rare case of small bowel adenocarcinoma complicating coeliac disease
title_full_unstemmed A rare case of small bowel adenocarcinoma complicating coeliac disease
title_short A rare case of small bowel adenocarcinoma complicating coeliac disease
title_sort rare case of small bowel adenocarcinoma complicating coeliac disease
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9238299/
https://www.ncbi.nlm.nih.gov/pubmed/35774478
http://dx.doi.org/10.1093/jscr/rjac300
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