Cargando…
A Collaborative Initiative to Establish Genomic Biomarkers for Assessing Tumorigenic Potential to Reduce Reliance on Conventional Rodent Carcinogenicity Studies
There is growing recognition across broad sectors of the scientific community that use of genomic biomarkers has the potential to reduce the need for conventional rodent carcinogenicity studies of industrial chemicals, agrochemicals, and pharmaceuticals through a weight-of-evidence approach. These b...
Autores principales: | Corton, J Christopher, Mitchell, Constance A, Auerbach, Scott, Bushel, Pierre, Ellinger-Ziegelbauer, Heidrun, Escobar, Patricia A, Froetschl, Roland, Harrill, Alison H, Johnson, Kamin, Klaunig, James E, Pandiri, Arun R, Podtelezhnikov, Alexei A, Rager, Julia E, Tanis, Keith Q, van der Laan, Jan Willem, Vespa, Alisa, Yauk, Carole L, Pettit, Syril D, Sistare, Frank D |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9238304/ https://www.ncbi.nlm.nih.gov/pubmed/35404422 http://dx.doi.org/10.1093/toxsci/kfac041 |
Ejemplares similares
-
TGx-DDI, a Transcriptomic Biomarker for Genotoxicity Hazard Assessment of Pharmaceuticals and Environmental Chemicals
por: Li, Heng-Hong, et al.
Publicado: (2019) -
Integrated Genotoxicity Testing of three anti-infective drugs using the TGx-DDI transcriptomic biomarker and high-throughput CometChip(®) assay in TK6 cells
por: Buick, Julie K., et al.
Publicado: (2022) -
Applying genomics in regulatory toxicology: a report of the ECETOC workshop on omics threshold on non-adversity
por: Gant, Timothy W., et al.
Publicado: (2023) -
A Transformative Vision for an Omics-Based Regulatory Chemical Testing Paradigm
por: Johnson, Kamin J, et al.
Publicado: (2022) -
Evaluation of Toxicogenomics Approaches for Assessing the Risk of Nongenotoxic Carcinogenicity in Rat Liver
por: Eichner, Johannes, et al.
Publicado: (2014)