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RG100204, A Novel Aquaporin-9 Inhibitor, Reduces Septic Cardiomyopathy and Multiple Organ Failure in Murine Sepsis

Sepsis is caused by systemic infection and is a major health concern as it is the primary cause of death from infection. It is the leading cause of mortality worldwide and there are no specific effective treatments for sepsis. Gene deletion of the neutral solute channel Aquaporin 9 (AQP9) normalizes...

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Detalles Bibliográficos
Autores principales: Mohammad, Shireen, O’Riordan, Caroline E., Verra, Chiara, Aimaretti, Eleonora, Alves, Gustavo Ferreira, Dreisch, Klaus, Evenäs, Johan, Gena, Patrizia, Tesse, Angela, Rützler, Michael, Collino, Massimo, Calamita, Giuseppe, Thiemermann, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9238327/
https://www.ncbi.nlm.nih.gov/pubmed/35774785
http://dx.doi.org/10.3389/fimmu.2022.900906

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