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RG100204, A Novel Aquaporin-9 Inhibitor, Reduces Septic Cardiomyopathy and Multiple Organ Failure in Murine Sepsis
Sepsis is caused by systemic infection and is a major health concern as it is the primary cause of death from infection. It is the leading cause of mortality worldwide and there are no specific effective treatments for sepsis. Gene deletion of the neutral solute channel Aquaporin 9 (AQP9) normalizes...
Autores principales: | Mohammad, Shireen, O’Riordan, Caroline E., Verra, Chiara, Aimaretti, Eleonora, Alves, Gustavo Ferreira, Dreisch, Klaus, Evenäs, Johan, Gena, Patrizia, Tesse, Angela, Rützler, Michael, Collino, Massimo, Calamita, Giuseppe, Thiemermann, Christoph |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9238327/ https://www.ncbi.nlm.nih.gov/pubmed/35774785 http://dx.doi.org/10.3389/fimmu.2022.900906 |
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