Rapid and sensitive multiplex detection of COVID-19 antigens and antibody using electrochemical immunosensor-/aptasensor-enabled biochips

We report protein- and aptamer-based electrochemical biochips for low-cost, one-step, sensitive and accurate multiplex detection of SARS-CoV-2 spike (S) and nucleocapsid (N) proteins, and IgG antibody in unprocessed clinical samples, allowing citizens to achieve rapid diagnosis at home or in communi...

Descripción completa

Detalles Bibliográficos
Autores principales: Jiang, Fuze, Xiao, Zhen, Wang, Ting, Wang, Jiajia, Bie, Lihua, Saleh, Lanja, Frey, Kathrin, Zhang, Lianjun, Wang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9238363/
https://www.ncbi.nlm.nih.gov/pubmed/35678120
http://dx.doi.org/10.1039/d2cc01598f
_version_ 1784737033747431424
author Jiang, Fuze
Xiao, Zhen
Wang, Ting
Wang, Jiajia
Bie, Lihua
Saleh, Lanja
Frey, Kathrin
Zhang, Lianjun
Wang, Jing
author_facet Jiang, Fuze
Xiao, Zhen
Wang, Ting
Wang, Jiajia
Bie, Lihua
Saleh, Lanja
Frey, Kathrin
Zhang, Lianjun
Wang, Jing
author_sort Jiang, Fuze
collection PubMed
description We report protein- and aptamer-based electrochemical biochips for low-cost, one-step, sensitive and accurate multiplex detection of SARS-CoV-2 spike (S) and nucleocapsid (N) proteins, and IgG antibody in unprocessed clinical samples, allowing citizens to achieve rapid diagnosis at home or in community settings.
format Online
Article
Text
id pubmed-9238363
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher The Royal Society of Chemistry
record_format MEDLINE/PubMed
spelling pubmed-92383632022-07-22 Rapid and sensitive multiplex detection of COVID-19 antigens and antibody using electrochemical immunosensor-/aptasensor-enabled biochips Jiang, Fuze Xiao, Zhen Wang, Ting Wang, Jiajia Bie, Lihua Saleh, Lanja Frey, Kathrin Zhang, Lianjun Wang, Jing Chem Commun (Camb) Chemistry We report protein- and aptamer-based electrochemical biochips for low-cost, one-step, sensitive and accurate multiplex detection of SARS-CoV-2 spike (S) and nucleocapsid (N) proteins, and IgG antibody in unprocessed clinical samples, allowing citizens to achieve rapid diagnosis at home or in community settings. The Royal Society of Chemistry 2022-05-26 /pmc/articles/PMC9238363/ /pubmed/35678120 http://dx.doi.org/10.1039/d2cc01598f Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Jiang, Fuze
Xiao, Zhen
Wang, Ting
Wang, Jiajia
Bie, Lihua
Saleh, Lanja
Frey, Kathrin
Zhang, Lianjun
Wang, Jing
Rapid and sensitive multiplex detection of COVID-19 antigens and antibody using electrochemical immunosensor-/aptasensor-enabled biochips
title Rapid and sensitive multiplex detection of COVID-19 antigens and antibody using electrochemical immunosensor-/aptasensor-enabled biochips
title_full Rapid and sensitive multiplex detection of COVID-19 antigens and antibody using electrochemical immunosensor-/aptasensor-enabled biochips
title_fullStr Rapid and sensitive multiplex detection of COVID-19 antigens and antibody using electrochemical immunosensor-/aptasensor-enabled biochips
title_full_unstemmed Rapid and sensitive multiplex detection of COVID-19 antigens and antibody using electrochemical immunosensor-/aptasensor-enabled biochips
title_short Rapid and sensitive multiplex detection of COVID-19 antigens and antibody using electrochemical immunosensor-/aptasensor-enabled biochips
title_sort rapid and sensitive multiplex detection of covid-19 antigens and antibody using electrochemical immunosensor-/aptasensor-enabled biochips
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9238363/
https://www.ncbi.nlm.nih.gov/pubmed/35678120
http://dx.doi.org/10.1039/d2cc01598f
work_keys_str_mv AT jiangfuze rapidandsensitivemultiplexdetectionofcovid19antigensandantibodyusingelectrochemicalimmunosensoraptasensorenabledbiochips
AT xiaozhen rapidandsensitivemultiplexdetectionofcovid19antigensandantibodyusingelectrochemicalimmunosensoraptasensorenabledbiochips
AT wangting rapidandsensitivemultiplexdetectionofcovid19antigensandantibodyusingelectrochemicalimmunosensoraptasensorenabledbiochips
AT wangjiajia rapidandsensitivemultiplexdetectionofcovid19antigensandantibodyusingelectrochemicalimmunosensoraptasensorenabledbiochips
AT bielihua rapidandsensitivemultiplexdetectionofcovid19antigensandantibodyusingelectrochemicalimmunosensoraptasensorenabledbiochips
AT salehlanja rapidandsensitivemultiplexdetectionofcovid19antigensandantibodyusingelectrochemicalimmunosensoraptasensorenabledbiochips
AT freykathrin rapidandsensitivemultiplexdetectionofcovid19antigensandantibodyusingelectrochemicalimmunosensoraptasensorenabledbiochips
AT zhanglianjun rapidandsensitivemultiplexdetectionofcovid19antigensandantibodyusingelectrochemicalimmunosensoraptasensorenabledbiochips
AT wangjing rapidandsensitivemultiplexdetectionofcovid19antigensandantibodyusingelectrochemicalimmunosensoraptasensorenabledbiochips

Ejemplares similares