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Identification and Tetramer Structure of Hemin-Binding Protein SPD_0310 Linked to Iron Homeostasis and Virulence of Streptococcus pneumoniae

Iron and iron-containing compounds are essential for bacterial virulence and host infection. Hemin is an important supplement compound for bacterial survival in an iron-deficient environment. Despite strong interest in hemin metabolism, the detailed mechanism of hemin transportation in Gram-positive...

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Detalles Bibliográficos
Autores principales: Cao, Kun, Zhang, Tianlong, Li, Nan, Yang, Xiao-Yan, Ding, Jianping, He, Qing-Yu, Sun, Xuesong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9238395/
https://www.ncbi.nlm.nih.gov/pubmed/35414267
http://dx.doi.org/10.1128/msystems.00221-22