Cargando…
DNase 1 Protects From Increased Thrombin Generation and Venous Thrombosis During Aging: Cross‐Sectional Study in Mice and Humans
BACKGROUND: Human aging is associated with increased risk of thrombosis, but the mechanisms are poorly defined. We hypothesized that aging induces peroxide‐dependent release of neutrophil extracellular traps that contribute to thrombin generation and thrombosis. METHODS AND RESULTS: We studied C57BL...
Autores principales: | Kumar, Rahul, Sonkar, Vijay K., Swamy, Jagadish, Ahmed, Azaj, Sharathkumar, Anjali A., Pierce, Gary L., Dayal, Sanjana |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9238525/ https://www.ncbi.nlm.nih.gov/pubmed/35023342 http://dx.doi.org/10.1161/JAHA.121.021188 |
Ejemplares similares
-
D‐dimer, thrombin generation, and risk of a first venous thrombosis in the elderly
por: Wang, Huijie, et al.
Publicado: (2021) -
Thrombotic potential during pediatric acute lymphoblastic leukemia induction: Role of cell‐free DNA
por: Kumar, Rahul, et al.
Publicado: (2021) -
Genetic Determinants of Thrombin Generation and Their Relation to Venous Thrombosis: Results from the GAIT-2 Project
por: Martin-Fernandez, Laura, et al.
Publicado: (2016) -
Point-of-Care
Platform for Diagnosis of Venous Thrombosis
by Simultaneous Detection of Thrombin Generation and D-Dimer
in Human Plasma
por: Hu, Chunxiao, et al.
Publicado: (2022) -
Direct oral anticoagulants in pediatric venous thromboembolism: Review of approved products rivaroxaban and dabigatran
por: Al-Ghafry, Maha, et al.
Publicado: (2022)