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Bulbar Symptoms as an Unusual Presentation of Multiple Sclerosis: A Case Report

Multiple sclerosis (MS) is a complex multifactorial disease with different clinical manifestations. Bulbar symptoms such as dysarthria and dysphagia are common in MS patients with advanced secondary progressive disease. However, they are not common at disease onset. We present the case of a 17-year-...

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Autores principales: Kai, Martine, Matta, Christian, Jalkh, Georges, Abdallah, Youmna, Haddad, Fady, Abboud, Halim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SMC Media Srl 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9239017/
https://www.ncbi.nlm.nih.gov/pubmed/35774729
http://dx.doi.org/10.12890/2022_003377
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author Kai, Martine
Matta, Christian
Jalkh, Georges
Abdallah, Youmna
Haddad, Fady
Abboud, Halim
author_facet Kai, Martine
Matta, Christian
Jalkh, Georges
Abdallah, Youmna
Haddad, Fady
Abboud, Halim
author_sort Kai, Martine
collection PubMed
description Multiple sclerosis (MS) is a complex multifactorial disease with different clinical manifestations. Bulbar symptoms such as dysarthria and dysphagia are common in MS patients with advanced secondary progressive disease. However, they are not common at disease onset. We present the case of a 17-year-old male who initially presented with vomiting, dysarthria, and dysphagia. The investigations led to the diagnosis of MS, with an active lesion in the brainstem, more specifically in the area postrema region. Differential diagnoses were eliminated. The patient received intravenous methylprednisolone resulting in amelioration of symptoms. Treatment with fingolimod was started after discharge. The recognition of MS with atypical onsets is important to make an early accurate diagnosis and prescribe appropriate treatment for a disease known to be one of the most common causes of neurologic disability in young adults. LEARNING POINTS: Multiple sclerosis can have atypical presentations. Bulbar symptoms such as dysarthria and dysphagia can be initial symptoms of multiple sclerosis, although uncommon. Clinicians should be able to recognize multiple sclerosis with atypical onsets in order to make an early accurate diagnosis.
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spelling pubmed-92390172022-06-29 Bulbar Symptoms as an Unusual Presentation of Multiple Sclerosis: A Case Report Kai, Martine Matta, Christian Jalkh, Georges Abdallah, Youmna Haddad, Fady Abboud, Halim Eur J Case Rep Intern Med Articles Multiple sclerosis (MS) is a complex multifactorial disease with different clinical manifestations. Bulbar symptoms such as dysarthria and dysphagia are common in MS patients with advanced secondary progressive disease. However, they are not common at disease onset. We present the case of a 17-year-old male who initially presented with vomiting, dysarthria, and dysphagia. The investigations led to the diagnosis of MS, with an active lesion in the brainstem, more specifically in the area postrema region. Differential diagnoses were eliminated. The patient received intravenous methylprednisolone resulting in amelioration of symptoms. Treatment with fingolimod was started after discharge. The recognition of MS with atypical onsets is important to make an early accurate diagnosis and prescribe appropriate treatment for a disease known to be one of the most common causes of neurologic disability in young adults. LEARNING POINTS: Multiple sclerosis can have atypical presentations. Bulbar symptoms such as dysarthria and dysphagia can be initial symptoms of multiple sclerosis, although uncommon. Clinicians should be able to recognize multiple sclerosis with atypical onsets in order to make an early accurate diagnosis. SMC Media Srl 2022-05-18 /pmc/articles/PMC9239017/ /pubmed/35774729 http://dx.doi.org/10.12890/2022_003377 Text en © EFIM 2022 This article is licensed under a Commons Attribution Non-Commercial 4.0 License
spellingShingle Articles
Kai, Martine
Matta, Christian
Jalkh, Georges
Abdallah, Youmna
Haddad, Fady
Abboud, Halim
Bulbar Symptoms as an Unusual Presentation of Multiple Sclerosis: A Case Report
title Bulbar Symptoms as an Unusual Presentation of Multiple Sclerosis: A Case Report
title_full Bulbar Symptoms as an Unusual Presentation of Multiple Sclerosis: A Case Report
title_fullStr Bulbar Symptoms as an Unusual Presentation of Multiple Sclerosis: A Case Report
title_full_unstemmed Bulbar Symptoms as an Unusual Presentation of Multiple Sclerosis: A Case Report
title_short Bulbar Symptoms as an Unusual Presentation of Multiple Sclerosis: A Case Report
title_sort bulbar symptoms as an unusual presentation of multiple sclerosis: a case report
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9239017/
https://www.ncbi.nlm.nih.gov/pubmed/35774729
http://dx.doi.org/10.12890/2022_003377
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