Clot In Transit in a Patient with Protein S Deficiency

Clot in transit (CIT) is a rare condition in which a venous thromboembolism becomes lodged in the right heart. It is seen in up to 18% of patients with massive pulmonary embolism, and if left untreated, mortality rates are between 80% and 100%. The identification and management of CIT are crucial. H...

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Detalles Bibliográficos
Autores principales: Kashfi, Simon, Nasser, Mohamed Farhan, Soleiman, Aron, Sharma, Sapna, Koripalli, Venkata Sandeep, Sharma, Shorabh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SMC Media Srl 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9239027/
https://www.ncbi.nlm.nih.gov/pubmed/35774736
http://dx.doi.org/10.12890/2022_003355
Descripción
Sumario:Clot in transit (CIT) is a rare condition in which a venous thromboembolism becomes lodged in the right heart. It is seen in up to 18% of patients with massive pulmonary embolism, and if left untreated, mortality rates are between 80% and 100%. The identification and management of CIT are crucial. However, there are no current guidelines for the treatment of CIT. We present the case of a 44-year-old woman who was found to have CIT that was ultimately treated with medical management. LEARNING POINTS: Clot in transit (CIT) is a dangerous entity that must be promptly managed. Risk factors for CIT include a history of heart failure, a pre-existing central venous catheter and recent hospitalization. New interventions are emerging for the treatment of CIT.

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