Differential Functions of Individual Transcription Factor Binding Sites in the Tandem Repeats Found in Clinically Relevant cyp51A Promoters in Aspergillus fumigatus

Aspergillus fumigatus is the major filamentous fungal pathogen in humans. The gold standard treatment of A. fumigatus is based on azole drug use, but the appearance of azole-resistant isolates is increasing at an alarming rate. The cyp51A gene encodes the enzymatic target of azole drugs, and azole-r...

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Detalles Bibliográficos
Autores principales: Paul, Sanjoy, Verweij, Paul E., Melchers, Willem J. G., Moye-Rowley, W. Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Observation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9239056/
https://www.ncbi.nlm.nih.gov/pubmed/35467427
http://dx.doi.org/10.1128/mbio.00702-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9239056/
https://www.ncbi.nlm.nih.gov/pubmed/35467427
http://dx.doi.org/10.1128/mbio.00702-22

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