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Evaluation of a Selective Chemical Probe Validates That CK2 Mediates Neuroinflammation in a Human Induced Pluripotent Stem Cell-Derived Mircroglial Model

Novel treatments for neurodegenerative disorders are in high demand. It is imperative that new protein targets be identified to address this need. Characterization and validation of nascent targets can be accomplished very effectively using highly specific and potent chemical probes. Human induced p...

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Detalles Bibliográficos
Autores principales: Mishra, Swati, Kinoshita, Chizuru, Axtman, Alison D., Young, Jessica E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9239073/
https://www.ncbi.nlm.nih.gov/pubmed/35774866
http://dx.doi.org/10.3389/fnmol.2022.824956