Interferon Lambda Signals in Maternal Tissues to Exert Protective and Pathogenic Effects in a Gestational Stage-Dependent Manner

Interferon lambda (IFN-λ) (type III IFN) is constitutively secreted from human placental cells in culture and reduces Zika virus (ZIKV) transplacental transmission in mice. However, the roles of IFN-λ during healthy pregnancy and in restricting congenital infection remain unclear. Here, we used mice...

Descripción completa

Detalles Bibliográficos
Autores principales: Casazza, Rebecca L., Philip, Drake T., Lazear, Helen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9239100/
https://www.ncbi.nlm.nih.gov/pubmed/35471083
http://dx.doi.org/10.1128/mbio.03857-21

Ejemplares similares

Ejemplares similares