Setting the Stage for the Next Great Vaccine Success Story

In this Commentary, the article by Rosenfeld et al. “Cross-Reactive Antibody Responses against Nonpoliovirus Enteroviruses” is put into context of the historic poliovirus epidemics and resultant vaccination success story as it compares to the current state of acute flaccid myelitis; the relationship...

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Detalles Bibliográficos
Autor principal: Freeman, Megan Culler
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9239114/
https://www.ncbi.nlm.nih.gov/pubmed/35658549
http://dx.doi.org/10.1128/mbio.00457-22
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author Freeman, Megan Culler
author_facet Freeman, Megan Culler
author_sort Freeman, Megan Culler
collection PubMed
description In this Commentary, the article by Rosenfeld et al. “Cross-Reactive Antibody Responses against Nonpoliovirus Enteroviruses” is put into context of the historic poliovirus epidemics and resultant vaccination success story as it compares to the current state of acute flaccid myelitis; the relationship to nonpoliovirus enteroviruses (EVs), in particular EV-D68 and EV-A71; and the potential for successful vaccination strategies. The discovery of cross-protective antibody neutralization among polio and nonpolio enteroviruses, specifically EV-D68, opens future questions about EV-D68 vaccination strategies, circulation patterns of nonpolio enteroviruses, and the interpretation of EV-D68 serostudies.
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spelling pubmed-92391142022-06-29 Setting the Stage for the Next Great Vaccine Success Story Freeman, Megan Culler mBio Commentary In this Commentary, the article by Rosenfeld et al. “Cross-Reactive Antibody Responses against Nonpoliovirus Enteroviruses” is put into context of the historic poliovirus epidemics and resultant vaccination success story as it compares to the current state of acute flaccid myelitis; the relationship to nonpoliovirus enteroviruses (EVs), in particular EV-D68 and EV-A71; and the potential for successful vaccination strategies. The discovery of cross-protective antibody neutralization among polio and nonpolio enteroviruses, specifically EV-D68, opens future questions about EV-D68 vaccination strategies, circulation patterns of nonpolio enteroviruses, and the interpretation of EV-D68 serostudies. American Society for Microbiology 2022-06-06 /pmc/articles/PMC9239114/ /pubmed/35658549 http://dx.doi.org/10.1128/mbio.00457-22 Text en Copyright © 2022 Freeman. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Commentary
Freeman, Megan Culler
Setting the Stage for the Next Great Vaccine Success Story
title Setting the Stage for the Next Great Vaccine Success Story
title_full Setting the Stage for the Next Great Vaccine Success Story
title_fullStr Setting the Stage for the Next Great Vaccine Success Story
title_full_unstemmed Setting the Stage for the Next Great Vaccine Success Story
title_short Setting the Stage for the Next Great Vaccine Success Story
title_sort setting the stage for the next great vaccine success story
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9239114/
https://www.ncbi.nlm.nih.gov/pubmed/35658549
http://dx.doi.org/10.1128/mbio.00457-22
work_keys_str_mv AT freemanmeganculler settingthestageforthenextgreatvaccinesuccessstory

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