The Delta SARS-CoV-2 Variant of Concern Induces Distinct Pathogenic Patterns of Respiratory Disease in K18-hACE2 Transgenic Mice Compared to the Ancestral Strain from Wuhan

Compared to the original ancestral strain of SARS-CoV-2, the Delta variant of concern has shown increased transmissibility and resistance toward COVID-19 vaccines and therapies. However, the pathogenesis of the disease associated with Delta is still not clear. In this study, using K18-hACE2 transgen...

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Detalles Bibliográficos
Autores principales: Liu, Xiang, Mostafavi, Helen, Ng, Wern Hann, Freitas, Joseph R., King, Nicholas J. C., Zaid, Ali, Taylor, Adam, Mahalingam, Suresh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9239116/
https://www.ncbi.nlm.nih.gov/pubmed/35420469
http://dx.doi.org/10.1128/mbio.00683-22

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