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Human Metapneumovirus Phosphoprotein Independently Drives Phase Separation and Recruits Nucleoprotein to Liquid-Like Bodies
Human metapneumovirus (HMPV) inclusion bodies (IBs) are dynamic structures required for efficient viral replication and transcription. The minimum components needed to form IB-like structures in cells are the nucleoprotein (N) and the tetrameric phosphoprotein (P). HMPV P binds to the following two...
Autores principales: | Boggs, Kerri Beth, Edmonds, Kearstin, Cifuentes-Munoz, Nicolas, El Najjar, Farah, Ossandón, Conny, Roe, McKenna, Wu, Chao, Moncman, Carole L., Creamer, Trevor P., Amarasinghe, Gaya K., Leung, Daisy W., Dutch, Rebecca Ellis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9239117/ https://www.ncbi.nlm.nih.gov/pubmed/35536005 http://dx.doi.org/10.1128/mbio.01099-22 |
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