Salmonella Induces the cGAS-STING-Dependent Type I Interferon Response in Murine Macrophages by Triggering mtDNA Release

Salmonella enterica serovar Typhimurium (S. Typhimurium) elicited strong innate immune responses in macrophages. To activate innate immunity, pattern recognition receptors (PRRs) in host cells can recognize highly conserved pathogen-associated molecular patterns (PAMPs). Here, we showed that S. Typh...

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Detalles Bibliográficos
Autores principales: Xu, Lei, Li, Mengyuan, Yang, Yadong, Zhang, Chen, Xie, Zhen, Tang, Jingjing, Shi, Zhenkun, Chen, Shukun, Li, Guangzhe, Gu, Yanchao, Wang, Xiao, Zhang, Fuhua, Wang, Yao, Shen, Xihui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9239183/
https://www.ncbi.nlm.nih.gov/pubmed/35604097
http://dx.doi.org/10.1128/mbio.03632-21

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