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Generation of Mature DENVs via Genetic Modification and Directed Evolution

Maturation of dengue viruses (DENVs) alters the structure, immunity, and infectivity of the virion and highly mature particles represent the dominant form in vivo. The production of highly mature virions principally relies on the structure and function of the viral premature membrane protein (prM) a...

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Detalles Bibliográficos
Autores principales:	Tse, Longping V., Meganck, Rita M., Dong, Stephanie, Adams, Lily E., White, Laura J., Mallory, Michael L., Jadi, Ramesh, de Silva, Aravinda M., Baric, Ralph S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9239201/ https://www.ncbi.nlm.nih.gov/pubmed/35481749 http://dx.doi.org/10.1128/mbio.00386-22

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