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Activities and Structure-Function Analysis of Fission Yeast Inositol Pyrophosphate (IPP) Kinase-Pyrophosphatase Asp1 and Its Impact on Regulation of pho1 Gene Expression

Inositol pyrophosphates (IPPs) are signaling molecules that regulate cellular phosphate homeostasis in diverse eukaryal taxa. In fission yeast, mutations that increase 1,5-IP(8) derepress the PHO regulon while mutations that ablate IP(8) synthesis are PHO hyper-repressive. Fission yeast Asp1, the pr...

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Detalles Bibliográficos
Autores principales:	Benjamin, Bradley, Garg, Angad, Jork, Nikolaus, Jessen, Henning J., Schwer, Beate, Shuman, Stewart
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9239264/ https://www.ncbi.nlm.nih.gov/pubmed/35536002 http://dx.doi.org/10.1128/mbio.01034-22

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