The Translational Landscape of SARS-CoV-2-infected Cells Reveals Suppression of Innate Immune Genes

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) utilizes a number of strategies to modulate viral and host mRNA translation. Here, we used ribosome profiling in SARS-CoV-2-infected model cell lines and primary airway cells grown at an air-liquid interface to gain a deeper understanding...

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Detalles Bibliográficos
Autores principales: Puray-Chavez, Maritza, Lee, Nakyung, Tenneti, Kasyap, Wang, Yiqing, Vuong, Hung R., Liu, Yating, Horani, Amjad, Huang, Tao, Gunsten, Sean P., Case, James B., Yang, Wei, Diamond, Michael S., Brody, Steven L., Dougherty, Joseph, Kutluay, Sebla B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9239271/
https://www.ncbi.nlm.nih.gov/pubmed/35604092
http://dx.doi.org/10.1128/mbio.00815-22

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