Integration of the Salmonella Typhimurium Methylome and Transcriptome Reveals That DNA Methylation and Transcriptional Regulation Are Largely Decoupled under Virulence-Related Conditions

Despite being in a golden age of bacterial epigenomics, little work has systematically examined the plasticity and functional impacts of the bacterial DNA methylome. Here, we leveraged single-molecule, real-time sequencing (SMRT-seq) to examine the m(6)A DNA methylome of two Salmonella enterica sero...

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Detalles Bibliográficos
Autores principales: Bourgeois, Jeffrey S., Anderson, Caroline E., Wang, Liuyang, Modliszewski, Jennifer L., Chen, Wei, Schott, Benjamin H., Devos, Nicolas, Ko, Dennis C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9239280/
https://www.ncbi.nlm.nih.gov/pubmed/35658533
http://dx.doi.org/10.1128/mbio.03464-21

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