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Synergistic Therapeutic Effects of Low Dose Decitabine and NY-ESO-1 Specific TCR-T Cells for the Colorectal Cancer With Microsatellite Stability

Patients of colorectal cancer (CRC) with microsatellite stability (MSS) show poor clinical response and little beneficial result from the immune-checkpoint inhibitors, due to the ‘cold’ tumor microenvironment. Meanwhile, decitabine can drive the ‘cold’ microenvironment towards ‘hot’ in multiple ways...

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Detalles Bibliográficos
Autores principales:	Yu, Ganjun, Wang, Wenying, He, Xiaobo, Xu, Jia, Xu, Rongrong, Wan, Tao, Wu, Yanfeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9239344/ https://www.ncbi.nlm.nih.gov/pubmed/35774131 http://dx.doi.org/10.3389/fonc.2022.895103

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