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Wunderlich syndrome, an unexpected urological complication in a patient with coronavirus disease 2019 (COVID-19): A case report

We describe the first case of Wunderlich syndrome as a hemorrhagic complication in a patient with severe acute respiratory syndrome coronavirus 2 infection and acute respiratory distress syndrome. The possible underlying pathophysiological mechanisms have been extensively discussed. Emergency manage...

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Autores principales: Presicce, Fabrizio, Martini, Marco, Minisola, Francesco, Falavolti, Cristina, Filianoti, Alessio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9239352/
https://www.ncbi.nlm.nih.gov/pubmed/35782631
http://dx.doi.org/10.1097/CU9.0000000000000100
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author Presicce, Fabrizio
Martini, Marco
Minisola, Francesco
Falavolti, Cristina
Filianoti, Alessio
author_facet Presicce, Fabrizio
Martini, Marco
Minisola, Francesco
Falavolti, Cristina
Filianoti, Alessio
author_sort Presicce, Fabrizio
collection PubMed
description We describe the first case of Wunderlich syndrome as a hemorrhagic complication in a patient with severe acute respiratory syndrome coronavirus 2 infection and acute respiratory distress syndrome. The possible underlying pathophysiological mechanisms have been extensively discussed. Emergency management included selective angioembolization of the upper polar arterial branches of the left kidney and discontinuation of thromboprophylaxis. The patient was discharged after 18 days. No other localizations or local recurrence of bleeding occurred during the hospitalization. Our report suggests a broad spectrum of clinical manifestations in patients with coronavirus disease 2019. As observed in our clinical case, in addition to thrombotic complications, bleeding is a significant cause of morbidity in coronavirus disease 2019 patients. Further studies should determine whether these urological bleeding sequelae are a direct manifestation of the infection or an indirect effect of thromboprophylaxis.
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spelling pubmed-92393522022-06-28 Wunderlich syndrome, an unexpected urological complication in a patient with coronavirus disease 2019 (COVID-19): A case report Presicce, Fabrizio Martini, Marco Minisola, Francesco Falavolti, Cristina Filianoti, Alessio Curr Urol Special Topic: COVID-19 and Urology: Case Report We describe the first case of Wunderlich syndrome as a hemorrhagic complication in a patient with severe acute respiratory syndrome coronavirus 2 infection and acute respiratory distress syndrome. The possible underlying pathophysiological mechanisms have been extensively discussed. Emergency management included selective angioembolization of the upper polar arterial branches of the left kidney and discontinuation of thromboprophylaxis. The patient was discharged after 18 days. No other localizations or local recurrence of bleeding occurred during the hospitalization. Our report suggests a broad spectrum of clinical manifestations in patients with coronavirus disease 2019. As observed in our clinical case, in addition to thrombotic complications, bleeding is a significant cause of morbidity in coronavirus disease 2019 patients. Further studies should determine whether these urological bleeding sequelae are a direct manifestation of the infection or an indirect effect of thromboprophylaxis. Lippincott Williams & Wilkins 2022-06 2022-03-02 /pmc/articles/PMC9239352/ /pubmed/35782631 http://dx.doi.org/10.1097/CU9.0000000000000100 Text en Copyright © 2022 The Authors. Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) This article is made available via the PMC Open Access Subset for unrestricted re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the COVID-19 pandemic or until permissions are revoked in writing. Upon expiration of these permissions, PMC is granted a perpetual license to make this article available via PMC and Europe PMC, consistent with existing copyright protections.
spellingShingle Special Topic: COVID-19 and Urology: Case Report
Presicce, Fabrizio
Martini, Marco
Minisola, Francesco
Falavolti, Cristina
Filianoti, Alessio
Wunderlich syndrome, an unexpected urological complication in a patient with coronavirus disease 2019 (COVID-19): A case report
title Wunderlich syndrome, an unexpected urological complication in a patient with coronavirus disease 2019 (COVID-19): A case report
title_full Wunderlich syndrome, an unexpected urological complication in a patient with coronavirus disease 2019 (COVID-19): A case report
title_fullStr Wunderlich syndrome, an unexpected urological complication in a patient with coronavirus disease 2019 (COVID-19): A case report
title_full_unstemmed Wunderlich syndrome, an unexpected urological complication in a patient with coronavirus disease 2019 (COVID-19): A case report
title_short Wunderlich syndrome, an unexpected urological complication in a patient with coronavirus disease 2019 (COVID-19): A case report
title_sort wunderlich syndrome, an unexpected urological complication in a patient with coronavirus disease 2019 (covid-19): a case report
topic Special Topic: COVID-19 and Urology: Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9239352/
https://www.ncbi.nlm.nih.gov/pubmed/35782631
http://dx.doi.org/10.1097/CU9.0000000000000100
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