Cargando…

Human coronary microvascular contractile dysfunction associates with viable synthetic smooth muscle cells

AIMS: Coronary microvascular smooth muscle cells (SMCs) respond to luminal pressure by developing myogenic tone (MT), a process integral to the regulation of microvascular perfusion. The cellular mechanisms underlying poor myogenic reactivity in patients with heart valve disease are unknown and form...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dora, Kim A, Borysova, Lyudmyla, Ye, Xi, Powell, Chloe, Beleznai, Timea Z, Stanley, Christopher P, Bruno, Vito D, Starborg, Tobias, Johnson, Errin, Pielach, Anna, Taggart, Michael, Smart, Nicola, Ascione, Raimondo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9239576/ https://www.ncbi.nlm.nih.gov/pubmed/34173824 http://dx.doi.org/10.1093/cvr/cvab218

Ejemplares similares

Signaling and structures underpinning conducted vasodilation in human and porcine intramyocardial coronary arteries
por: Dora, Kim A., et al.
Publicado: (2022)

How calcium signals in myocytes and pericytes are integrated across in situ microvascular networks and control microvascular tone()
por: Borysova, Lyudmyla, et al.
Publicado: (2013)

Neuropeptide-Y causes coronary microvascular constriction and is associated with reduced ejection fraction following ST-elevation myocardial infarction
por: Herring, Neil, et al.
Publicado: (2019)

Smooth muscle gap-junctions allow propagation of intercellular Ca(2+) waves and vasoconstriction due to Ca(2+) based action potentials in rat mesenteric resistance arteries
por: Borysova, Lyudmyla, et al.
Publicado: (2018)

Evidence that NO/cGMP/PKG signalling cascade mediates endothelium dependent inhibition of IP(3)R mediated Ca(2+) oscillations in myocytes and pericytes of ureteric microvascular network in situ
por: Borysova, Lyudmyla, et al.
Publicado: (2015)

The cytoskeletal and contractile apparatus of smooth muscle: contraction bands and segmentation of the contractile elements
Publicado: (1990)

Dynamic Changes in Microvascular Density Can Predict Viable and Non-Viable Areas in High-Risk Neuroblastoma
por: Privitera, Laura, et al.
Publicado: (2023)

ULTRASTRUCTURAL STUDIES ON THE CONTRACTILE MECHANISM OF SMOOTH MUSCLE
por: Kelly, Robert E., et al.
Publicado: (1969)

THE ORGANIZATION OF CONTRACTILE FILAMENTS IN A MAMMALIAN SMOOTH MUSCLE
por: Rice, Robert V., et al.
Publicado: (1970)

Characterization of Contractile Machinery of Vascular Smooth Muscles in Hypertension
por: Yang, Qunhui, et al.
Publicado: (2021)

Store-operated Ca(2+) entry and depolarization explain the anomalous behaviour of myometrial SR: Effects of SERCA inhibition on electrical activity, Ca(2+) and force
por: Noble, Debbie, et al.
Publicado: (2014)

Differences in cellular contractile protein contents among porcine smooth muscles: evidence for variation in the contractile system
Publicado: (1978)

Ultrastructural Analysis of Cell Envelope and Accumulation of Lipid Inclusions in Clinical Mycobacterium tuberculosis Isolates from Sputum, Oxidative Stress, and Iron Deficiency
por: Vijay, Srinivasan, et al.
Publicado: (2018)

Effects of Polyamines on Contractility of Guinea-Pig Gastric Smooth Muscle
por: Kim, Young Chul, et al.
Publicado: (2007)

Hydrochlorothiazide Potentiates Contractile Activity of Mouse Cavernosal Smooth Muscle
por: Gagliano-Jucá, Thiago, et al.
Publicado: (2016)

Carotid smooth muscle contractility changes after severe burn
por: DeSpain, Kevin, et al.
Publicado: (2021)

Quercetin affects uterine smooth muscle contractile activity in gilts
por: Zygmuntowicz, Aleksandra, et al.
Publicado: (2021)

Microvascular Dysfunction in Peripheral Artery Disease: Is Heat Therapy a Viable Treatment?
por: Anderson, Cody P., et al.
Publicado: (2021)

Microvascular pericyte contractility in vitro: comparison with other cells of the vascular wall
Publicado: (1987)

Contractile Protein Expression and Phosphorylation and Contractility of Gastric Smooth Muscles from Obese Patients and Patients with Obesity and Diabetes
por: Li, Wen, et al.
Publicado: (2018)

Annuloplasty for mitral valve repair in degenerative disease: to be flexible or to be rigid? That’s still the question
por: Bruno, Vito Domenico, et al.
Publicado: (2020)

Endothelial Nitric Oxide Suppresses Action-Potential-Like Transient Spikes and Vasospasm in Small Resistance Arteries
por: Smith, Josh F., et al.
Publicado: (2020)

Force-Generating Capacity and Contractile Protein Content of Arterial Smooth Muscle
por: Murphy, R. A., et al.
Publicado: (1974)

Effects of 17β-oestradiol on rat detrusor smooth muscle contractility
por: Valeri, Aurora, et al.
Publicado: (2009)

Caveolin-3 Promotes a Vascular Smooth Muscle Contractile Phenotype
por: Gutierrez-Pajares, Jorge L., et al.
Publicado: (2015)

The role of contractile unit reorganization in force generation in airway smooth muscle
por: Brook, B. S., et al.
Publicado: (2014)

Regulation of PKC Autophosphorylation by Calponin in Contractile Vascular Smooth Muscle Tissue
por: Kim, Hak Rim, et al.
Publicado: (2013)

Contractility Measurements of Human Uterine Smooth Muscle to Aid Drug Development
por: Arrowsmith, Sarah, et al.
Publicado: (2018)

Direct optogenetic stimulation of smooth muscle cells to control gastric contractility
por: Vogt, Markus, et al.
Publicado: (2021)

The effect of cinnamaldehyde on the contractility of bovine isolated gastrointestinal smooth muscle preparations
por: Arbati, Alireza, et al.
Publicado: (2021)

Methamphetamine-induced cardiomyopathy causing severe mitral valve regurgitation
por: Bruno, Vito D., et al.
Publicado: (2014)

Methionine Enhances the Contractile Activity of Human Colon Circular Smooth Muscle In Vitro
por: Choe, Eun Kyung, et al.
Publicado: (2012)

Opportunities to Target Specific Contractile Abnormalities with Smooth Muscle Protein Kinase Inhibitors
por: Ulke-Lemée, Annegret, et al.
Publicado: (2010)

Dual effect of quercetin on rat isolated portal vein smooth muscle contractility
por: Chiwororo, Witness DH, et al.
Publicado: (2010)

Caveolin-1 is required for contractile phenotype expression by airway smooth muscle cells
por: Gosens, Reinoud, et al.
Publicado: (2011)

Neuropilin 1 Is Essential for Gastrointestinal Smooth Muscle Contractility and Motility in Aged Mice
por: Yamaji, Maiko, et al.
Publicado: (2015)

Evaluation of mouse urinary bladder smooth muscle for diurnal differences in contractile properties
por: White, Rachel S., et al.
Publicado: (2015)

Mechanisms underlying the pathogenesis of hyper-contractility of bronchial smooth muscle in allergic asthma
por: Sakai, Hiroyasu, et al.
Publicado: (2017)

Hypermethylation of mitochondrial DNA in vascular smooth muscle cells impairs cell contractility
por: Liu, Yue-Feng, et al.
Publicado: (2020)

Lenvatinib halts aortic aneurysm growth by restoring smooth muscle cell contractility
por: Busch, Albert, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_6r8e2kg6o42uls862rdplut7bm