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Personalized treatment of malignant tumors during pregnancy
The combination of pregnancy and cancer is a challenge for the patient and a problematic clinical dilemma for the doctor. In this retrospective observational cohort study, we have tried to analyze our experience in the management of such patients. This review includes 41 patients with malignant neop...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9239643/ https://www.ncbi.nlm.nih.gov/pubmed/35777052 http://dx.doi.org/10.1097/MD.0000000000029803 |
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author | Ulrikh, E. Kalinina, E. Dikareva, E. Komlichenko, E. Li, O. Zhamborova, O. Rizhinashvili, I. Dzharbaeva, A. Govorov, I. Artemenko, V. Bezrukikh, V. Salogub, G. Pervunina, T. Urmancheeva, A. |
author_facet | Ulrikh, E. Kalinina, E. Dikareva, E. Komlichenko, E. Li, O. Zhamborova, O. Rizhinashvili, I. Dzharbaeva, A. Govorov, I. Artemenko, V. Bezrukikh, V. Salogub, G. Pervunina, T. Urmancheeva, A. |
author_sort | Ulrikh, E. |
collection | PubMed |
description | The combination of pregnancy and cancer is a challenge for the patient and a problematic clinical dilemma for the doctor. In this retrospective observational cohort study, we have tried to analyze our experience in the management of such patients. This review includes 41 patients with malignant neoplasms detected during pregnancy who received treatment at the Almazov National Medical Research Centre from 2015-2021. The majority of patients received treatment during pregnancy (n=26, 63.4%): chemotherapy – 19 (46.3%) (in 2 cases in combination with surgery), surgical treatment – 7 (17, 1%) patients. In most cases, delivery was at term (n=28, 68.3%). All children born at term were mature and had no growth restriction, regardless of whether the mothers received treatment during pregnancy or not. When detecting cancer during pregnancy, an immediate follow-up examination is required to assess the extent of the tumor and current fetal state. If pregnancy prolongation is requested, the treatment should not be postponed, except for systemic chemotherapy in the first trimester of pregnancy, pelvic radiation at any term. |
format | Online Article Text |
id | pubmed-9239643 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Lippincott Williams & Wilkins |
record_format | MEDLINE/PubMed |
spelling | pubmed-92396432022-06-30 Personalized treatment of malignant tumors during pregnancy Ulrikh, E. Kalinina, E. Dikareva, E. Komlichenko, E. Li, O. Zhamborova, O. Rizhinashvili, I. Dzharbaeva, A. Govorov, I. Artemenko, V. Bezrukikh, V. Salogub, G. Pervunina, T. Urmancheeva, A. Medicine (Baltimore) Research Article The combination of pregnancy and cancer is a challenge for the patient and a problematic clinical dilemma for the doctor. In this retrospective observational cohort study, we have tried to analyze our experience in the management of such patients. This review includes 41 patients with malignant neoplasms detected during pregnancy who received treatment at the Almazov National Medical Research Centre from 2015-2021. The majority of patients received treatment during pregnancy (n=26, 63.4%): chemotherapy – 19 (46.3%) (in 2 cases in combination with surgery), surgical treatment – 7 (17, 1%) patients. In most cases, delivery was at term (n=28, 68.3%). All children born at term were mature and had no growth restriction, regardless of whether the mothers received treatment during pregnancy or not. When detecting cancer during pregnancy, an immediate follow-up examination is required to assess the extent of the tumor and current fetal state. If pregnancy prolongation is requested, the treatment should not be postponed, except for systemic chemotherapy in the first trimester of pregnancy, pelvic radiation at any term. Lippincott Williams & Wilkins 2022-06-30 /pmc/articles/PMC9239643/ /pubmed/35777052 http://dx.doi.org/10.1097/MD.0000000000029803 Text en Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY) (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Ulrikh, E. Kalinina, E. Dikareva, E. Komlichenko, E. Li, O. Zhamborova, O. Rizhinashvili, I. Dzharbaeva, A. Govorov, I. Artemenko, V. Bezrukikh, V. Salogub, G. Pervunina, T. Urmancheeva, A. Personalized treatment of malignant tumors during pregnancy |
title | Personalized treatment of malignant tumors during pregnancy |
title_full | Personalized treatment of malignant tumors during pregnancy |
title_fullStr | Personalized treatment of malignant tumors during pregnancy |
title_full_unstemmed | Personalized treatment of malignant tumors during pregnancy |
title_short | Personalized treatment of malignant tumors during pregnancy |
title_sort | personalized treatment of malignant tumors during pregnancy |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9239643/ https://www.ncbi.nlm.nih.gov/pubmed/35777052 http://dx.doi.org/10.1097/MD.0000000000029803 |
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