CAMSAP2 organizes a γ-tubulin-independent microtubule nucleation centre through phase separation

Microtubules are dynamic polymers consisting of αβ-tubulin heterodimers. The initial polymerization process, called microtubule nucleation, occurs spontaneously via αβ-tubulin. Since a large energy barrier prevents microtubule nucleation in cells, the γ-tubulin ring complex is recruited to the centr...

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Detalles Bibliográficos
Autores principales: Imasaki, Tsuyoshi, Kikkawa, Satoshi, Niwa, Shinsuke, Saijo-Hamano, Yumiko, Shigematsu, Hideki, Aoyama, Kazuhiro, Mitsuoka, Kaoru, Shimizu, Takahiro, Aoki, Mari, Sakamoto, Ayako, Tomabechi, Yuri, Sakai, Naoki, Shirouzu, Mikako, Taguchi, Shinya, Yamagishi, Yosuke, Setsu, Tomiyoshi, Sakihama, Yoshiaki, Nitta, Eriko, Takeichi, Masatoshi, Nitta, Ryo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9239687/
https://www.ncbi.nlm.nih.gov/pubmed/35762204
http://dx.doi.org/10.7554/eLife.77365

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