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Systemic Relapse in a Young Adult Patient with Primary CNS Diffuse Large B-Cell Lymphoma

Primary central nervous system diffuse large B-cell lymphoma (PCNS-DLBCL) is a rare form of non-Hodgkin's lymphoma, characterized by an aggressive disease course. While CNS relapse is common, systemic relapse is rare with no consensus on optimal treatment. This paper presents an unusual case of...

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Detalles Bibliográficos
Autores principales: Khorasanchi, Adam, Benson, Zachary, Hall, Misty, Ebadirad, Nelya, Gharavi, Mohammad H., Willard, Patrick, Chimzar, Miranda, McKay, John, Simmons, Gary, Yazbeck, Victor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9239761/
https://www.ncbi.nlm.nih.gov/pubmed/35774056
http://dx.doi.org/10.1155/2022/7139661
Descripción
Sumario:Primary central nervous system diffuse large B-cell lymphoma (PCNS-DLBCL) is a rare form of non-Hodgkin's lymphoma, characterized by an aggressive disease course. While CNS relapse is common, systemic relapse is rare with no consensus on optimal treatment. This paper presents an unusual case of advanced PCNS-DLBCL with systemic relapse, including adrenal gland involvement. A review of the existing literature and a discussion on the management of systemic relapse in PCNS-DLBCL is also provided.