Systemic Relapse in a Young Adult Patient with Primary CNS Diffuse Large B-Cell Lymphoma

Primary central nervous system diffuse large B-cell lymphoma (PCNS-DLBCL) is a rare form of non-Hodgkin's lymphoma, characterized by an aggressive disease course. While CNS relapse is common, systemic relapse is rare with no consensus on optimal treatment. This paper presents an unusual case of...

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Autores principales: Khorasanchi, Adam, Benson, Zachary, Hall, Misty, Ebadirad, Nelya, Gharavi, Mohammad H., Willard, Patrick, Chimzar, Miranda, McKay, John, Simmons, Gary, Yazbeck, Victor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9239761/
https://www.ncbi.nlm.nih.gov/pubmed/35774056
http://dx.doi.org/10.1155/2022/7139661
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author Khorasanchi, Adam
Benson, Zachary
Hall, Misty
Ebadirad, Nelya
Gharavi, Mohammad H.
Willard, Patrick
Chimzar, Miranda
McKay, John
Simmons, Gary
Yazbeck, Victor
author_facet Khorasanchi, Adam
Benson, Zachary
Hall, Misty
Ebadirad, Nelya
Gharavi, Mohammad H.
Willard, Patrick
Chimzar, Miranda
McKay, John
Simmons, Gary
Yazbeck, Victor
author_sort Khorasanchi, Adam
collection PubMed
description Primary central nervous system diffuse large B-cell lymphoma (PCNS-DLBCL) is a rare form of non-Hodgkin's lymphoma, characterized by an aggressive disease course. While CNS relapse is common, systemic relapse is rare with no consensus on optimal treatment. This paper presents an unusual case of advanced PCNS-DLBCL with systemic relapse, including adrenal gland involvement. A review of the existing literature and a discussion on the management of systemic relapse in PCNS-DLBCL is also provided.
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spelling pubmed-92397612022-06-29 Systemic Relapse in a Young Adult Patient with Primary CNS Diffuse Large B-Cell Lymphoma Khorasanchi, Adam Benson, Zachary Hall, Misty Ebadirad, Nelya Gharavi, Mohammad H. Willard, Patrick Chimzar, Miranda McKay, John Simmons, Gary Yazbeck, Victor Case Rep Hematol Case Report Primary central nervous system diffuse large B-cell lymphoma (PCNS-DLBCL) is a rare form of non-Hodgkin's lymphoma, characterized by an aggressive disease course. While CNS relapse is common, systemic relapse is rare with no consensus on optimal treatment. This paper presents an unusual case of advanced PCNS-DLBCL with systemic relapse, including adrenal gland involvement. A review of the existing literature and a discussion on the management of systemic relapse in PCNS-DLBCL is also provided. Hindawi 2022-06-21 /pmc/articles/PMC9239761/ /pubmed/35774056 http://dx.doi.org/10.1155/2022/7139661 Text en Copyright © 2022 Adam Khorasanchi et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Khorasanchi, Adam
Benson, Zachary
Hall, Misty
Ebadirad, Nelya
Gharavi, Mohammad H.
Willard, Patrick
Chimzar, Miranda
McKay, John
Simmons, Gary
Yazbeck, Victor
Systemic Relapse in a Young Adult Patient with Primary CNS Diffuse Large B-Cell Lymphoma
title Systemic Relapse in a Young Adult Patient with Primary CNS Diffuse Large B-Cell Lymphoma
title_full Systemic Relapse in a Young Adult Patient with Primary CNS Diffuse Large B-Cell Lymphoma
title_fullStr Systemic Relapse in a Young Adult Patient with Primary CNS Diffuse Large B-Cell Lymphoma
title_full_unstemmed Systemic Relapse in a Young Adult Patient with Primary CNS Diffuse Large B-Cell Lymphoma
title_short Systemic Relapse in a Young Adult Patient with Primary CNS Diffuse Large B-Cell Lymphoma
title_sort systemic relapse in a young adult patient with primary cns diffuse large b-cell lymphoma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9239761/
https://www.ncbi.nlm.nih.gov/pubmed/35774056
http://dx.doi.org/10.1155/2022/7139661
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