Cargando…

Bioactive Components and Potential Mechanism Prediction of Kui Jie Kang against Ulcerative Colitis via Systematic Pharmacology and UPLC-QE-MS Analysis

Kui Jie Kang (KJK)—a traditional Chinese medicine—has demonstrated clinical therapeutic efficacy against ulcerative colitis (UC). However, the active compounds and their underlying mechanisms have not yet been fully characterized. Therefore, the current study sought to identify the volatile compound...

Descripción completa

Detalles Bibliográficos
Autores principales:	He, Jinbiao, Wan, Chunping, Li, Xiaosi, Zhang, Zishu, Yang, Yu, Wang, Huaning, Qi, Yan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9239780/ https://www.ncbi.nlm.nih.gov/pubmed/35774753 http://dx.doi.org/10.1155/2022/9122315

Ejemplares similares

A Systems Pharmacology Approach to Determine Active Compounds and Action Mechanisms of Xipayi KuiJie’an enema for Treatment of Ulcerative colitis
por: Yu, Wei, et al.
Publicado: (2017)

Uygur Medicine Xipayi Kui Jie’an Affects Gene Expression profiles in intestinal tissue Lesions in a Rat Model of Ulcerative Colitis
por: Yunusi, Kurexi, et al.
Publicado: (2015)

Kui Jie Tong Ameliorates Ulcerative Colitis by Regulating Gut Microbiota and NLRP3/Caspase-1 Classical Pyroptosis Signaling Pathway
por: Xue, Shigui, et al.
Publicado: (2022)

Investigating the Active Substance and Mechanism of San-Jiu-Wei-Tai Granules via UPLC-QE-Orbitrap-MS and Network Pharmacology
por: Yu, Gengyuan, et al.
Publicado: (2022)

Investigation of the Potential Phlorotannins and Mechanism of Six Brown Algae in Treating Type II Diabetes Mellitus Based on Biological Activity, UPLC-QE-MS/MS, and Network Pharmacology
por: Chen, Jialiang, et al.
Publicado: (2023)

Pharmacokinetic Study of Four Major Bioactive Components of Liandan Xiaoyan Formula in Ulcerative Colitis and Control Rats Using UPLC-MS/MS
por: Zhang, Kaihui, et al.
Publicado: (2022)

A Mechanism Exploration for the Yi-Fei-San-Jie Formula against Non-Small-Cell Lung Cancer Based on UPLC-MS/MS, Network Pharmacology, and In Silico Verification
por: Hu, Leihao, et al.
Publicado: (2023)

UPLC–MS/MS and Network Pharmacology-Based Analysis of Bioactive Anti-Depression Compounds in Betel Nut
por: Yang, Yunjia, et al.
Publicado: (2021)

Identification of Bioactive Components of Stephania epigaea Lo and Their Potential Therapeutic Targets by UPLC-MS/MS and Network Pharmacology
por: Li, Xingyu, et al.
Publicado: (2022)

UPLC-QE-Orbitrap-Based Cell Metabolomics and Network Pharmacology to Reveal the Mechanism of N-Benzylhexadecanamide Isolated from Maca (Lepidium meyenii Walp.) against Testicular Dysfunction
por: Zhang, Kai-Yue, et al.
Publicado: (2023)

Comparative analysis of oligosaccharides in the milk of human and animals by using LC-QE-HF-MS
por: Li, Rui, et al.
Publicado: (2023)

US QE and the Indian Bond Market
por: Paul, Moumita, et al.
Publicado: (2021)

Effect of Huangqin Tang on Urine Metabolic Profile in Rats with Ulcerative Colitis Based on UPLC-Q-Exactive Orbitrap MS
por: Wang, Dunfang, et al.
Publicado: (2020)

Protective Effects of Protopanaxatriol Saponins on Ulcerative Colitis in Mouse Based on UPLC-Q/TOF-MS Serum and Colon Metabolomics
por: Wu, Fulin, et al.
Publicado: (2022)

Identification of Serum Metabolomics Characteristics in Patients with Stable Angina Pectoris Using UHPLC-QE-MS
por: Zhou, Yufei, et al.
Publicado: (2022)

Metabolomics Analysis of PK-15 Cells with Pseudorabies Virus Infection Based on UHPLC-QE-MS
por: Liu, Panrao, et al.
Publicado: (2022)

Analysis of Bioactive Components in the Fruit, Roots, and Leaves of Alpinia oxyphylla by UPLC-MS/MS
por: Ying, Li, et al.
Publicado: (2021)

Quantification of twenty pharmacologically active dyes in water samples using UPLC-MS/MS
por: Tkaczyk-Wlizło, Angelika, et al.
Publicado: (2022)

Composition and Bioactivity of a Modified Huang-Lian-Jie-Du Decoction
por: Lin, Mei-Yi, et al.
Publicado: (2022)

Retracted: Identification of Serum Metabolomics Characteristics in Patients with Stable Angina Pectoris Using UHPLC-QE-MS
por: Methods in Medicine, Computational and Mathematical
Publicado: (2023)

Determination of Bioactive Components in Chinese Herbal Formulae and Pharmacokinetics of Rhein in Rats by UPLC-MS/MS
por: Hou, Mei-Ling, et al.
Publicado: (2014)

QnAs with Le Kang
por: Ahmed, Farooq
Publicado: (2023)

Pharmacokinetic and Metabolism Studies of Curculigoside C by UPLC-MS/MS and UPLC-QTOF-MS
por: Wu, Di, et al.
Publicado: (2018)

Minu xi kuatsura chichjána kui anima xi bantiya yajura : qué cosa dice mi tata, seres que se transforman /
por: Velasco Casimiro, Filogonio, 1986-
Publicado: (2013)

UPLC-TOF-MS Characterization and Identification of Bioactive Iridoids in Cornus mas Fruit
por: Deng, Shixin, et al.
Publicado: (2013)

Determination of nine bioactive phenolic components usually found in apple juice by simultaneous UPLC‐MS/MS
por: Li, Qiu‐lin, et al.
Publicado: (2023)

Wall Street QE vs. Main Street Lending()
por: Cardamone, Dario, et al.
Publicado: (2023)

Exploring the Potential Mechanism of Qi-Shen-Di-Huang Drug Formulary for Myasthenia Gravis (MG) based on UHPLC-QE-MS Network Pharmacology and Molecular Docking Techniques
por: Zhang, Yibin, et al.
Publicado: (2022)

Response to Mahatanan and Kang: It's Complicated
por: Molina, Kyle C, et al.
Publicado: (2023)

UHPLC-ESI-QE-Orbitrap-MS based metabolomics reveals the antioxidant mechanism of icaritin on mice with cerebral ischemic reperfusion
por: Tang, Yunfeng, et al.
Publicado: (2023)

Identifying absorbable bioactive constituents of Yupingfeng Powder acting on COVID-19 through integration of UPLC-Q/TOF-MS and network pharmacology analysis
por: Wang, Linyan, et al.
Publicado: (2022)

Pharmacokinetic and Metabolism Studies of 12-Riboside-Pseudoginsengenin DQ by UPLC-MS/MS and UPLC-QTOF-MS(E)
por: Wang, Zhenzhou, et al.
Publicado: (2018)

Insights into the metabolic profiling of Polygonati Rhizoma fermented by Lactiplantibacillus plantarum under aerobic and anaerobic conditions using a UHPLC-QE-MS/MS system
por: Wang, ZiLing, et al.
Publicado: (2023)

QE data for Pb/Nb deposited photo cathode samples
por: Sekutowicz, J
Publicado: (2010)

Pursue the truth, devote to education: Chen Hua-Kui, a respectable educator and pioneer of China’s soil microbiology
por: Chen, Doudou, et al.
Publicado: (2016)

Based on Network Pharmacology to Explore the Potential Bioactive Compounds and Mechanisms of Zuojin Pill for the Treatment of Ulcerative Colitis
por: Wei, Ying, et al.
Publicado: (2021)

Development of a validated UPLC–qTOF-MS/MS method for determination of bioactive constituent from Glycyrrhiza glabra
por: Gupta, D.K., et al.
Publicado: (2013)

Simultaneous Determination of Three Bioactive Constituents from Bletilla striata by UPLC-MS/MS and Application of the Technique to Pharmacokinetic Analyses
por: Chen, Hao, et al.
Publicado: (2019)

First person – Jie Sun
Publicado: (2020)

Comparative Analysis of Oligosaccharides in Breast Milk and Feces of Breast-Fed Infants by Using LC-QE-HF-MS: A Communication
por: Li, Rui, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_2ugq8k5essonnes33nhon7058u