Cargando…

Interleukin-10-Modified Adipose-Derived Mesenchymal Stem Cells Prevent Hypertrophic Scar Formation via Regulating the Biological Characteristics of Fibroblasts and Inflammation

Hypertrophic scar causes serious functional and cosmetic problem, but no treatment method is known to achieve a satisfactory therapeutic effect. However, mesenchymal stem cells show a possible cure prospect. Here, we investigated the effect of interleukin-10-modified adipose-derived mesenchymal stem...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xie, Fang, Teng, Li, Lu, Jianjian, Xu, Jiajie, Zhang, Chao, Yang, Liya, Ma, Xiaoyang, Zhao, Minghao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9239815/ https://www.ncbi.nlm.nih.gov/pubmed/35774067 http://dx.doi.org/10.1155/2022/6368311

Ejemplares similares

Adipose-derived mesenchymal stem cells inhibit cell proliferation and migration and suppress extracellular matrix synthesis in hypertrophic-scar and keloid fibroblasts
por: Xie, Fang, et al.
Publicado: (2021)

Adipose-Derived Mesenchymal Stem Cells Alleviate Hypertrophic Scar by Inhibiting Bioactivity and Inducing Apoptosis in Hypertrophic Scar Fibroblasts
por: Li, Shiyi, et al.
Publicado: (2022)

Shikonin promotes hypertrophic scar repair by autophagy of hypertrophic scar-derived fibroblasts
por: Zhang, Qing, et al.
Publicado: (2023)

Inhibition of sphingosine kinase 2 attenuates hypertrophic scar formation via upregulation of Smad7 in human hypertrophic scar fibroblasts
por: Zeng, Jian, et al.
Publicado: (2020)

Anti-Fibrotic Actions of Interleukin-10 against Hypertrophic Scarring by Activation of PI3K/AKT and STAT3 Signaling Pathways in Scar-Forming Fibroblasts
por: Shi, Jihong, et al.
Publicado: (2014)

Multipotent stromal cells/mesenchymal stem cells and fibroblasts combine to minimize skin hypertrophic scarring
por: Yates, Cecelia C., et al.
Publicado: (2017)

Comparison between Stromal Vascular Fraction and Adipose Mesenchymal Stem Cells in Remodeling Hypertrophic Scars
por: Domergue, Sophie, et al.
Publicado: (2016)

Emerging Role of IL-10 in Hypertrophic Scars
por: Sun, Zi-Li, et al.
Publicado: (2020)

The role of macrophages in the formation of hypertrophic scars and keloids
por: Xu, Xiangwen, et al.
Publicado: (2020)

Downregulation of CFTR Is Involved in the Formation of Hypertrophic Scars
por: Zhou, Yiwen, et al.
Publicado: (2020)

Therapeutic Strategies by Regulating Interleukin Family to Suppress Inflammation in Hypertrophic Scar and Keloid
por: Zhang, Dan, et al.
Publicado: (2021)

miR-495 inhibits the growth of fibroblasts in hypertrophic scars
por: Guo, Bingyu, et al.
Publicado: (2019)

Effect of THBS1 on the Biological Function of Hypertrophic Scar Fibroblasts
por: Jiang, D., et al.
Publicado: (2020)

Use of Adipose Stem Cells Against Hypertrophic Scarring or Keloid
por: Chen, Hongbo, et al.
Publicado: (2022)

Mesenchymal stem cell therapy in hypertrophic and keloid scars
por: Bojanic, Christine, et al.
Publicado: (2021)

Direct and Indirect Roles of Macrophages in Hypertrophic Scar Formation
por: Feng, Yi, et al.
Publicado: (2019)

Cuprous oxide nanoparticles reduces hypertrophic scarring by inducing fibroblast apoptosis
por: Xiao, Yongqiang, et al.
Publicado: (2019)

Abstract 3: Identification of Fibroblast Subtypes during Hypertrophic Scar Development
por: Kuehlmann, Britta, et al.
Publicado: (2017)

Interleukin-31, Interleukin-31RA, and OSMR Expression Levels in Post-burn Hypertrophic Scars
por: Lee, Mi Young, et al.
Publicado: (2018)

Role of Mitogen-Activated Protein Kinases in the Formation of Hypertrophic Scar with Model of Lipopolysaccharide Stimulated Skin Fibroblast Cells
por: Wang, Weidong, et al.
Publicado: (2018)

Effects of transplanted adipose derived stem cells on the expressions of α-SMA and DCN in fibroblasts of hypertrophic scar tissues in rabbit ears
por: Chu, Haihan, et al.
Publicado: (2018)

The Roles of Inflammation in Keloid and Hypertrophic Scars
por: Wang, Zheng-Cai, et al.
Publicado: (2020)

The interplay of fibroblasts, the extracellular matrix, and inflammation in scar formation
por: Moretti, Leandro, et al.
Publicado: (2021)

Paclitaxel reduces formation of hypertrophic scars in the rabbit ear model
por: Huang, Li-ping, et al.
Publicado: (2015)

Targeted apoptosis of myofibroblasts by elesclomol inhibits hypertrophic scar formation
por: Feng, Yi, et al.
Publicado: (2020)

Effect of Hypertrophic Scar Fibroblast-Derived Exosomes on Keratinocytes of Normal Human Skin
por: Cui, Hui Song, et al.
Publicado: (2023)

Inhibition of hypertrophic scar formation with oral asiaticoside treatment in a rabbit ear scar model
por: Huang, Jia, et al.
Publicado: (2021)

Mechanotransduction in skin wound healing and scar formation: Potential therapeutic targets for controlling hypertrophic scarring
por: Yin, Jiayi, et al.
Publicado: (2022)

sncRNA changes induced by tension in hypertrophic scar: sncRNAs in hypertrophic scar
por: Yin, Chuang, et al.
Publicado: (2022)

Arctigenin suppresses fibroblast activity and extracellular matrix deposition in hypertrophic scarring by reducing inflammation and oxidative stress
por: Jiang, Ling, et al.
Publicado: (2020)

Hypertrophic Scar Formation Following Burns and Trauma: New Approaches to Treatment
por: Aarabi, Shahram, et al.
Publicado: (2007)

Process of Hypertrophic Scar Formation: Expression of Eukaryotic Initiation Factor 6
por: Yang, Qing-Qing, et al.
Publicado: (2015)

Lycorine Inhibits Hypertrophic Scar Formation by Inducing ROS-Mediated Apoptosis
por: Dong, Yunxian, et al.
Publicado: (2022)

HDAC5-mediated Smad7 silencing through MEF2A is critical for fibroblast activation and hypertrophic scar formation
por: Gao, Ya, et al.
Publicado: (2022)

Fibroblasts in Scar Formation: Biology and Clinical Translation
por: Qian, Huan, et al.
Publicado: (2022)

Extracellular Vesicles Derived From Human Adipose-Derived Stem Cell Prevent the Formation of Hypertrophic Scar in a Rabbit Model
por: Zhu, Yuan-zheng, et al.
Publicado: (2020)

MicroRNA-21 Regulates hTERT via PTEN in Hypertrophic Scar Fibroblasts
por: Zhu, Hua-Yu, et al.
Publicado: (2014)

Smad-binding decoy reduces extracellular matrix expression in human hypertrophic scar fibroblasts
por: Fan, Chen, et al.
Publicado: (2020)

Silicone Gel for Hypertrophic Scars
por: Wiwanitkit, Viroj
Publicado: (2010)

Update on hypertrophic scar treatment
por: Rabello, Felipe Bettini, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_3angut851oev1frh849jvr8c95