MANTA and MANTA-RAy: Rationale and Design of Trials Evaluating Effects of Filgotinib on Semen Parameters in Patients with Inflammatory Diseases

INTRODUCTION: The phase 2 MANTA and MANTA-RAy studies were developed in consultation with global regulatory authorities to investigate potential impacts of filgotinib, a Janus kinase 1 preferential inhibitor, on semen parameters in men with active inflammatory diseases. Here we describe the methods...

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Detalles Bibliográficos
Autores principales: Hellstrom, Wayne J. G., Dolhain, Radboud J. E. M., Ritter, Timothy E., Watkins, Timothy R., Arterburn, Sarah J., Dekkers, Goele, Gillen, Angi, Tonussi, Caroline, Gilles, Leen, Oortwijn, Alessandra, Van Beneden, Katrien, de Vries, Dick E., Sikka, Suresh C., Vanderschueren, Dirk, Reinisch, Walter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2022
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9239965/
https://www.ncbi.nlm.nih.gov/pubmed/35614292
http://dx.doi.org/10.1007/s12325-022-02168-4

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