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TNF-α Triggers RIP1/FADD/Caspase-8-Mediated Apoptosis of Astrocytes and RIP3/MLKL-Mediated Necroptosis of Neurons Induced by Angiostrongylus cantonensis Infection

Angiostrongylus cantonensis (AC) can cause severe eosinophilic meningitis or encephalitis in non-permissive hosts accompanied by apoptosis and necroptosis of brain cells. However, the explicit underlying molecular basis of apoptosis and necroptosis upon AC infection has not yet been elucidated. To d...

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Detalles Bibliográficos
Autores principales: Zhou, Hongli, Zhou, Minyu, Hu, Yue, Limpanon, Yanin, Ma, Yubin, Huang, Ping, Dekumyoy, Paron, Maleewong, Wanchai, Lv, Zhiyue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9239968/
https://www.ncbi.nlm.nih.gov/pubmed/33683530
http://dx.doi.org/10.1007/s10571-021-01063-w