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Orthologs of human circulating miRNAs associated with hepatocellular carcinoma are elevated in mouse plasma months before tumour detection

Research examining the potential for circulating miRNA to serve as markers for preneoplastic lesions or early-stage hepatocellular carcinoma (HCC) is hindered by the difficulties of obtaining samples from asymptomatic individuals. As a surrogate for human samples, we identified hub miRNAs in gene co...

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Detalles Bibliográficos
Autores principales: Ding, Liang-Hao, Fallgren, Christina M., Yu, Yongjia, McCarthy, Maureen, Edmondson, Elijah F., Ullrich, Robert L., Weil, Michael. M., Story, Michael D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9240017/
https://www.ncbi.nlm.nih.gov/pubmed/35764780
http://dx.doi.org/10.1038/s41598-022-15061-5