Cargando…

Environmental variables and genome-environment interactions predicting IBD diagnosis in large UK cohort

A combination of genetic susceptibility and environmental exposure is thought to cause inflammatory bowel disease (IBD), but the non-genetic component remains poorly characterized. We therefore undertook a search for environmental variables and gene-environment interactions associated with future IB...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Alan Z., Jostins-Dean, Luke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9240024/ https://www.ncbi.nlm.nih.gov/pubmed/35764673 http://dx.doi.org/10.1038/s41598-022-13222-0

Ejemplares similares

Dispatches from the functional phase of genome biology
por: Jostins, Luke
Publicado: (2012)

Graphical Model Selection for Gaussian Conditional Random Fields in the Presence of Latent Variables
por: Frot, Benjamin, et al.
Publicado: (2018)

Association of IBD specific treatment and prevalence of pain in the Swiss IBD cohort study
por: Bon, Lorenz, et al.
Publicado: (2019)

Biomarkers in IBD: What to Utilize for the Diagnosis?
por: D’Incà, Renata, et al.
Publicado: (2023)

Solid Organ Transplantation in Patients with Inflammatory Bowel Diseases (IBD): Analysis of Transplantation Outcome and IBD Activity in a Large Single Center Cohort
por: Schnitzler, Fabian, et al.
Publicado: (2015)

Guiding longitudinal sampling in IBD cohorts
por: Vázquez-Baeza, Yoshiki, et al.
Publicado: (2018)

Genotype-by-environment interactions inferred from genetic effects on phenotypic variability in the UK Biobank
por: Wang, Huanwei, et al.
Publicado: (2019)

Trinculo: Bayesian and frequentist multinomial logistic regression for genome-wide association studies of multi-category phenotypes
por: Jostins, Luke, et al.
Publicado: (2016)

Weight and BMI Patterns in a Biologicals-Treated IBD Cohort
por: Kaazan, P., et al.
Publicado: (2022)

IBD in the Time of COVID19
por: Moss, Alan, et al.
Publicado: (2020)

An Effective Filter for IBD Detection in Large Data Sets
por: Huang, Lin, et al.
Publicado: (2014)

Dietary Habit Is Associated with Depression and Intelligence: An Observational and Genome-Wide Environmental Interaction Analysis in the UK Biobank Cohort
por: Cheng, Bolun, et al.
Publicado: (2021)

Cohort Profile: UK COSMOS—a UK cohort for study of environment and health
por: Toledano, Mireille B, et al.
Publicado: (2017)

Su1483: COVID-19 VACCINES ARE HIGHLY EFFECTIVE IN PATIENTS WITH IBD: OUTCOMES FROM THE SCOUT IBD COHORT
por: Hong, Simon J., et al.
Publicado: (2022)

Gut microbiota is associated with bone mineral density: an observational and genome-wide environmental interaction analysis in the UK Biobank cohort
por: Cheng, Bolun, et al.
Publicado: (2021)

Use, Durability, and Risks for Discontinuation of Initial and Subsequent Biologics in a Large Pediatric-Onset IBD Cohort
por: Kaplan, Jess L., et al.
Publicado: (2023)

Personalized genealogical history of UK individuals inferred from biobank-scale IBD segments
por: Naseri, Ardalan, et al.
Publicado: (2021)

Nutritional Assessment in Inflammatory Bowel Disease (IBD)—Development of the Groningen IBD Nutritional Questionnaires (GINQ)
por: Peters, Vera, et al.
Publicado: (2019)

Bridges to excellence quality indicators in inflammatory bowel disease (IBD): differences between IBD and non-IBD gastroenterologists
por: Bilal, Mohammad, et al.
Publicado: (2017)

Not All Fibers Are Born Equal; Variable Response to Dietary Fiber Subtypes in IBD
por: Armstrong, Heather, et al.
Publicado: (2021)

Interpersonal variability of the human gut virome confounds disease signal detection in IBD
por: Stockdale, Stephen R., et al.
Publicado: (2023)

A retrospective cohort study: pre‐operative oral enteral nutritional optimisation for Crohnʼs disease in a UK tertiary IBD centre
por: Meade, Susanna, et al.
Publicado: (2022)

Accurate genome-wide phasing from IBD data
por: Noto, Keith, et al.
Publicado: (2022)

Genome-wide by environment interaction studies of maternal smoking and educational score in UK biobank
por: Huang, Huimei, et al.
Publicado: (2023)

Next-generation sequencing and the era of personal Y genomes
por: Ayub, Qasim, et al.
Publicado: (2010)

Leaky Gut in IBD: Intestinal Barrier–Gut Microbiota Interaction
por: Yu, Shunying, et al.
Publicado: (2022)

IBD: An Interpretable Backdoor-Detection Method via Multivariate Interactions
por: Xu, Yixiao, et al.
Publicado: (2022)

COVID-19 in IBD: The experience of a single tertiary IBD center
por: Rizzello, Fernando, et al.
Publicado: (2021)

Reverse engineering a gene network using an asynchronous parallel evolution strategy
por: Jostins, Luke, et al.
Publicado: (2010)

Genome-Wide Analysis of Dental Caries Variability Reveals Genotype-by-Environment Interactions
por: Zou, Tianyu, et al.
Publicado: (2023)

Gene–obesogenic environment interactions in the UK Biobank study
por: Tyrrell, Jessica, et al.
Publicado: (2017)

Genomic profiling of T-cell activation suggests increased sensitivity of memory T cells to CD28 costimulation
por: Glinos, Dafni A., et al.
Publicado: (2020)

Western and Carnivorous Dietary Patterns are Associated with Greater Likelihood of IBD Development in a Large Prospective Population-based Cohort
por: Peters, Vera, et al.
Publicado: (2021)

Challenges in the diagnosis and management of IBD: a sub-Saharan African perspective
por: Watermeyer, Gill, et al.
Publicado: (2023)

Food Additives, a Key Environmental Factor in the Development of IBD through Gut Dysbiosis
por: Raoul, Pauline, et al.
Publicado: (2022)

Zebrafish model for IBD
Publicado: (2011)

IBD considerations in spondyloarthritis
por: Di Jiang, Caroline, et al.
Publicado: (2020)

The Impact of PPARγ Genetic Variants on IBD Susceptibility and IBD Disease Course
por: Mwinyi, Jessica, et al.
Publicado: (2012)

Risk of Adverse Pregnancy Outcomes for Women with IBD in an Expert IBD Antenatal Clinic
por: Lever, Gillian, et al.
Publicado: (2022)

Influence of Genetics, Immunity and the Microbiome on the Prognosis of Inflammatory Bowel Disease (IBD Prognosis Study): the protocol for a Copenhagen IBD Inception Cohort Study
por: Attauabi, Mohamed, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_66duvtd3u7vkrcn4ob0fhhl4sc