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Enhancement of Phosphorylation and Transport Activity of the Neuronal Glutamate Transporter Excitatory Amino Acid Transporter 3 by C3bot and a 26mer C3bot Peptide
In primary murine hippocampal neurons we investigated the regulation of EAAT3-mediated glutamate transport by the Clostridium botulinum C3 transferase C3bot and a 26mer peptide derived from full length protein. Incubation with either enzyme-competent C3bot or enzyme-deficient C3bot(156–181) peptide...
Autores principales: | Piepgras, Johannes, Rohrbeck, Astrid, Just, Ingo, Bittner, Stefan, Ahnert-Hilger, Gudrun, Höltje, Markus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9240211/ https://www.ncbi.nlm.nih.gov/pubmed/35783090 http://dx.doi.org/10.3389/fncel.2022.860823 |
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