Cargando…
Pediatric Acute Severe Hepatitis of Unknown Origin: What is New?
Globally, there are emerging cases of acute severe hepatitis of unknown origin in children. These cases have gathered increasing attention, owing to the development of acute liver failure in some cases that resulted in liver transplantation. This review briefly summarizes the outbreak and diagnostic...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
XIA & HE Publishing Inc.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9240247/ https://www.ncbi.nlm.nih.gov/pubmed/35836759 http://dx.doi.org/10.14218/JCTH.2022.00247 |
_version_ | 1784737494089072640 |
---|---|
author | Li, Jing Hu, Wei Zhang, Ji-Yuan Wang, Fu-Sheng |
author_facet | Li, Jing Hu, Wei Zhang, Ji-Yuan Wang, Fu-Sheng |
author_sort | Li, Jing |
collection | PubMed |
description | Globally, there are emerging cases of acute severe hepatitis of unknown origin in children. These cases have gathered increasing attention, owing to the development of acute liver failure in some cases that resulted in liver transplantation. This review briefly summarizes the outbreak and diagnostic criteria of the disease. We further discuss the possible causes and related mechanisms underlying its occurrence and progression, and analyze the challenges in management. Finally, this review emphasizes patient management in clinical settings and a combination of efforts to unmask the disease. |
format | Online Article Text |
id | pubmed-9240247 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | XIA & HE Publishing Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-92402472022-07-13 Pediatric Acute Severe Hepatitis of Unknown Origin: What is New? Li, Jing Hu, Wei Zhang, Ji-Yuan Wang, Fu-Sheng J Clin Transl Hepatol Review Article Globally, there are emerging cases of acute severe hepatitis of unknown origin in children. These cases have gathered increasing attention, owing to the development of acute liver failure in some cases that resulted in liver transplantation. This review briefly summarizes the outbreak and diagnostic criteria of the disease. We further discuss the possible causes and related mechanisms underlying its occurrence and progression, and analyze the challenges in management. Finally, this review emphasizes patient management in clinical settings and a combination of efforts to unmask the disease. XIA & HE Publishing Inc. 2022-06-28 2022-06-20 /pmc/articles/PMC9240247/ /pubmed/35836759 http://dx.doi.org/10.14218/JCTH.2022.00247 Text en © 2022 Authors. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0), permitting all non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Li, Jing Hu, Wei Zhang, Ji-Yuan Wang, Fu-Sheng Pediatric Acute Severe Hepatitis of Unknown Origin: What is New? |
title | Pediatric Acute Severe Hepatitis of Unknown Origin: What is New? |
title_full | Pediatric Acute Severe Hepatitis of Unknown Origin: What is New? |
title_fullStr | Pediatric Acute Severe Hepatitis of Unknown Origin: What is New? |
title_full_unstemmed | Pediatric Acute Severe Hepatitis of Unknown Origin: What is New? |
title_short | Pediatric Acute Severe Hepatitis of Unknown Origin: What is New? |
title_sort | pediatric acute severe hepatitis of unknown origin: what is new? |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9240247/ https://www.ncbi.nlm.nih.gov/pubmed/35836759 http://dx.doi.org/10.14218/JCTH.2022.00247 |
work_keys_str_mv | AT lijing pediatricacuteseverehepatitisofunknownoriginwhatisnew AT huwei pediatricacuteseverehepatitisofunknownoriginwhatisnew AT zhangjiyuan pediatricacuteseverehepatitisofunknownoriginwhatisnew AT wangfusheng pediatricacuteseverehepatitisofunknownoriginwhatisnew |