A Randomized Controlled Dose-Escalation Study of LY06006, a Recombinant Humanized Monoclonal Antibody to RANKL, in Chinese Healthy Adults

Background: This study was conducted to explore the safety, tolerance, pharmacokinetics, pharmacodynamics, and immunogenicity of LY06006, a recombinant humanized monoclonal antibody to RANKL, when administrated subcutaneously in Chinese healthy adults. Research design and methods: This was a randomi...

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Detalles Bibliográficos
Autores principales: Niu, Suping, Chen, Min, Yan, Diqin, Liu, Xiangxing, Guo, Shuren, Ou, Lun, Fan, Huaying, Lv, Jie, Wang, Qian, Dong, Wenliang, Xia, Lin, Wang, Simin, Liu, Gang, Gu, Qun, Guo, Danjie, Liu, Hongxia, Rao, Huiying, Zheng, Qingshan, Nie, Xiaoyan, Song, Haifeng, Fang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9240259/
https://www.ncbi.nlm.nih.gov/pubmed/35784742
http://dx.doi.org/10.3389/fphar.2022.893166

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