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Differential IL-12 signaling induces human natural killer cell activating receptor-mediated ligand-specific expansion

IL-12 is an essential cytokine involved in the generation of memory or memory-like NK cells. Mouse cytomegalovirus infection triggers NK receptor-induced, ligand-specific IL-12–dependent NK cell expansion, yet specific IL-12 stimulation ex vivo leading to NK cell proliferation and expansion is not e...

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Detalles Bibliográficos
Autores principales:	Shemesh, Avishai, Pickering, Harry, Roybal, Kole T., Lanier, Lewis L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9240274/ https://www.ncbi.nlm.nih.gov/pubmed/35758909 http://dx.doi.org/10.1084/jem.20212434

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