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Review: The Development of Risk Factors and Cytokines in Retinal Vein Occlusion
Retinal vein occlusion (RVO) is the second most prevalent retinal disease. Despite this, the pathogenic mechanisms and risk factors are not entirely clear. In this article, we review recent publications on the classification, pathogenesis, risk factors, ischemic changes, cytokines, and vital complic...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9240302/ https://www.ncbi.nlm.nih.gov/pubmed/35783660 http://dx.doi.org/10.3389/fmed.2022.910600 |
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author | Tang, Yi Cheng, Yan Wang, Shuo Wang, Yongjie Liu, Pengjia Wu, Hong |
author_facet | Tang, Yi Cheng, Yan Wang, Shuo Wang, Yongjie Liu, Pengjia Wu, Hong |
author_sort | Tang, Yi |
collection | PubMed |
description | Retinal vein occlusion (RVO) is the second most prevalent retinal disease. Despite this, the pathogenic mechanisms and risk factors are not entirely clear. In this article, we review recent publications on the classification, pathogenesis, risk factors, ischemic changes, cytokines, and vital complications of RVO. Risk factors and cytokines are important for exploring the mechanisms and new treatment targets. Furthermore, risk factors are interrelated, making RVO mechanisms more complex. Cytokines act as powerful mediators of pathological conditions, such as inflammation, neovascularization, and macular edema. This review aims to summarize the updated knowledge on risk factors, cytokines of RVO and signaling in order to provide valuable insight on managing the disease. |
format | Online Article Text |
id | pubmed-9240302 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-92403022022-06-30 Review: The Development of Risk Factors and Cytokines in Retinal Vein Occlusion Tang, Yi Cheng, Yan Wang, Shuo Wang, Yongjie Liu, Pengjia Wu, Hong Front Med (Lausanne) Medicine Retinal vein occlusion (RVO) is the second most prevalent retinal disease. Despite this, the pathogenic mechanisms and risk factors are not entirely clear. In this article, we review recent publications on the classification, pathogenesis, risk factors, ischemic changes, cytokines, and vital complications of RVO. Risk factors and cytokines are important for exploring the mechanisms and new treatment targets. Furthermore, risk factors are interrelated, making RVO mechanisms more complex. Cytokines act as powerful mediators of pathological conditions, such as inflammation, neovascularization, and macular edema. This review aims to summarize the updated knowledge on risk factors, cytokines of RVO and signaling in order to provide valuable insight on managing the disease. Frontiers Media S.A. 2022-06-15 /pmc/articles/PMC9240302/ /pubmed/35783660 http://dx.doi.org/10.3389/fmed.2022.910600 Text en Copyright © 2022 Tang, Cheng, Wang, Wang, Liu and Wu. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Medicine Tang, Yi Cheng, Yan Wang, Shuo Wang, Yongjie Liu, Pengjia Wu, Hong Review: The Development of Risk Factors and Cytokines in Retinal Vein Occlusion |
title | Review: The Development of Risk Factors and Cytokines in Retinal Vein Occlusion |
title_full | Review: The Development of Risk Factors and Cytokines in Retinal Vein Occlusion |
title_fullStr | Review: The Development of Risk Factors and Cytokines in Retinal Vein Occlusion |
title_full_unstemmed | Review: The Development of Risk Factors and Cytokines in Retinal Vein Occlusion |
title_short | Review: The Development of Risk Factors and Cytokines in Retinal Vein Occlusion |
title_sort | review: the development of risk factors and cytokines in retinal vein occlusion |
topic | Medicine |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9240302/ https://www.ncbi.nlm.nih.gov/pubmed/35783660 http://dx.doi.org/10.3389/fmed.2022.910600 |
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