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Review: The Development of Risk Factors and Cytokines in Retinal Vein Occlusion

Retinal vein occlusion (RVO) is the second most prevalent retinal disease. Despite this, the pathogenic mechanisms and risk factors are not entirely clear. In this article, we review recent publications on the classification, pathogenesis, risk factors, ischemic changes, cytokines, and vital complic...

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Autores principales: Tang, Yi, Cheng, Yan, Wang, Shuo, Wang, Yongjie, Liu, Pengjia, Wu, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9240302/
https://www.ncbi.nlm.nih.gov/pubmed/35783660
http://dx.doi.org/10.3389/fmed.2022.910600
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author Tang, Yi
Cheng, Yan
Wang, Shuo
Wang, Yongjie
Liu, Pengjia
Wu, Hong
author_facet Tang, Yi
Cheng, Yan
Wang, Shuo
Wang, Yongjie
Liu, Pengjia
Wu, Hong
author_sort Tang, Yi
collection PubMed
description Retinal vein occlusion (RVO) is the second most prevalent retinal disease. Despite this, the pathogenic mechanisms and risk factors are not entirely clear. In this article, we review recent publications on the classification, pathogenesis, risk factors, ischemic changes, cytokines, and vital complications of RVO. Risk factors and cytokines are important for exploring the mechanisms and new treatment targets. Furthermore, risk factors are interrelated, making RVO mechanisms more complex. Cytokines act as powerful mediators of pathological conditions, such as inflammation, neovascularization, and macular edema. This review aims to summarize the updated knowledge on risk factors, cytokines of RVO and signaling in order to provide valuable insight on managing the disease.
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spelling pubmed-92403022022-06-30 Review: The Development of Risk Factors and Cytokines in Retinal Vein Occlusion Tang, Yi Cheng, Yan Wang, Shuo Wang, Yongjie Liu, Pengjia Wu, Hong Front Med (Lausanne) Medicine Retinal vein occlusion (RVO) is the second most prevalent retinal disease. Despite this, the pathogenic mechanisms and risk factors are not entirely clear. In this article, we review recent publications on the classification, pathogenesis, risk factors, ischemic changes, cytokines, and vital complications of RVO. Risk factors and cytokines are important for exploring the mechanisms and new treatment targets. Furthermore, risk factors are interrelated, making RVO mechanisms more complex. Cytokines act as powerful mediators of pathological conditions, such as inflammation, neovascularization, and macular edema. This review aims to summarize the updated knowledge on risk factors, cytokines of RVO and signaling in order to provide valuable insight on managing the disease. Frontiers Media S.A. 2022-06-15 /pmc/articles/PMC9240302/ /pubmed/35783660 http://dx.doi.org/10.3389/fmed.2022.910600 Text en Copyright © 2022 Tang, Cheng, Wang, Wang, Liu and Wu. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Medicine
Tang, Yi
Cheng, Yan
Wang, Shuo
Wang, Yongjie
Liu, Pengjia
Wu, Hong
Review: The Development of Risk Factors and Cytokines in Retinal Vein Occlusion
title Review: The Development of Risk Factors and Cytokines in Retinal Vein Occlusion
title_full Review: The Development of Risk Factors and Cytokines in Retinal Vein Occlusion
title_fullStr Review: The Development of Risk Factors and Cytokines in Retinal Vein Occlusion
title_full_unstemmed Review: The Development of Risk Factors and Cytokines in Retinal Vein Occlusion
title_short Review: The Development of Risk Factors and Cytokines in Retinal Vein Occlusion
title_sort review: the development of risk factors and cytokines in retinal vein occlusion
topic Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9240302/
https://www.ncbi.nlm.nih.gov/pubmed/35783660
http://dx.doi.org/10.3389/fmed.2022.910600
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