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Mobilization-based chemotherapy-free engraftment of gene-edited human hematopoietic stem cells

Hematopoietic stem/progenitor cell gene therapy (HSPC-GT) is proving successful to treat several genetic diseases. HSPCs are mobilized, harvested, genetically corrected ex vivo, and infused, after the administration of toxic myeloablative conditioning to deplete the bone marrow (BM) for the modified...

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Detalles Bibliográficos
Autores principales:	Omer-Javed, Attya, Pedrazzani, Gabriele, Albano, Luisa, Ghaus, Sherash, Latroche, Claire, Manzi, Maura, Ferrari, Samuele, Fiumara, Martina, Jacob, Aurelien, Vavassori, Valentina, Nonis, Alessandro, Canarutto, Daniele, Naldini, Luigi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9240327/ https://www.ncbi.nlm.nih.gov/pubmed/35617958 http://dx.doi.org/10.1016/j.cell.2022.04.039

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