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COVID-19 in a tertiary paediatric centre in Portugal: a single-centre retrospective study
OBJECTIVE: To describe the demographic, clinical, laboratory and imaging features of the first 300 SARS-CoV-2-infected children presenting to a tertiary paediatric centre in Portugal. DESIGN: Single-centre, retrospective, descriptive study of paediatric patients who had a confirmed SARS-CoV-2 infect...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9240441/ https://www.ncbi.nlm.nih.gov/pubmed/36053601 http://dx.doi.org/10.1136/bmjpo-2021-001252 |
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author | Silva, Tiago Milheiro Garcia, Ana Margarida Gouveia, Catarina Candeias, Flora Brito, Maria João |
author_facet | Silva, Tiago Milheiro Garcia, Ana Margarida Gouveia, Catarina Candeias, Flora Brito, Maria João |
author_sort | Silva, Tiago Milheiro |
collection | PubMed |
description | OBJECTIVE: To describe the demographic, clinical, laboratory and imaging features of the first 300 SARS-CoV-2-infected children presenting to a tertiary paediatric centre in Portugal. DESIGN: Single-centre, retrospective, descriptive study of paediatric patients who had a confirmed SARS-CoV-2 infection from 7 March to 20 September 2020. SETTING: Tertiary paediatric referral centre (Hospital Dona Estefânia, Lisbon, Portugal). PATIENTS: 18 years or younger. MAIN OUTCOME MEASURES: Incidence, mortality, age of infection, clinical characteristics, treatment prescribed and outcome. RESULTS: Three hundred patients with confirmed COVID-19 presented to the centre. One hundred and seventeen (39%) patients were admitted to the hospital: 69 with COVID-19 and 48 for other reasons. The most common symptoms in children admitted with COVID-19 were fever (49) and cough (38). Six patients required intensive care. Two children died and seven reported short-term sequelae. CONCLUSIONS: COVID-19 is usually a mild disease in children, but a small proportion of patients develop severe and critical disease. Fatal outcomes were rare and only occurred in children with severe previous medical conditions. |
format | Online Article Text |
id | pubmed-9240441 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | BMJ Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-92404412022-06-30 COVID-19 in a tertiary paediatric centre in Portugal: a single-centre retrospective study Silva, Tiago Milheiro Garcia, Ana Margarida Gouveia, Catarina Candeias, Flora Brito, Maria João BMJ Paediatr Open Infectious Diseases OBJECTIVE: To describe the demographic, clinical, laboratory and imaging features of the first 300 SARS-CoV-2-infected children presenting to a tertiary paediatric centre in Portugal. DESIGN: Single-centre, retrospective, descriptive study of paediatric patients who had a confirmed SARS-CoV-2 infection from 7 March to 20 September 2020. SETTING: Tertiary paediatric referral centre (Hospital Dona Estefânia, Lisbon, Portugal). PATIENTS: 18 years or younger. MAIN OUTCOME MEASURES: Incidence, mortality, age of infection, clinical characteristics, treatment prescribed and outcome. RESULTS: Three hundred patients with confirmed COVID-19 presented to the centre. One hundred and seventeen (39%) patients were admitted to the hospital: 69 with COVID-19 and 48 for other reasons. The most common symptoms in children admitted with COVID-19 were fever (49) and cough (38). Six patients required intensive care. Two children died and seven reported short-term sequelae. CONCLUSIONS: COVID-19 is usually a mild disease in children, but a small proportion of patients develop severe and critical disease. Fatal outcomes were rare and only occurred in children with severe previous medical conditions. BMJ Publishing Group 2022-06-27 /pmc/articles/PMC9240441/ /pubmed/36053601 http://dx.doi.org/10.1136/bmjpo-2021-001252 Text en © Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) . |
spellingShingle | Infectious Diseases Silva, Tiago Milheiro Garcia, Ana Margarida Gouveia, Catarina Candeias, Flora Brito, Maria João COVID-19 in a tertiary paediatric centre in Portugal: a single-centre retrospective study |
title | COVID-19 in a tertiary paediatric centre in Portugal: a single-centre retrospective study |
title_full | COVID-19 in a tertiary paediatric centre in Portugal: a single-centre retrospective study |
title_fullStr | COVID-19 in a tertiary paediatric centre in Portugal: a single-centre retrospective study |
title_full_unstemmed | COVID-19 in a tertiary paediatric centre in Portugal: a single-centre retrospective study |
title_short | COVID-19 in a tertiary paediatric centre in Portugal: a single-centre retrospective study |
title_sort | covid-19 in a tertiary paediatric centre in portugal: a single-centre retrospective study |
topic | Infectious Diseases |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9240441/ https://www.ncbi.nlm.nih.gov/pubmed/36053601 http://dx.doi.org/10.1136/bmjpo-2021-001252 |
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