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Safety and efficacy of suprachoroidal triamcinolone acetonide for the management of serous choroidal detachment prior to rhegmatogenous retinal detachment surgery: A Pilot study

PURPOSE: To study the safety and efficacy of pre-operative suprachoroidal triamcinolone acetonide (SCTA) for achieving reduction/resolution of serous choroidal detachment (CD) associated with rhegmatogenous retinal detachment (RRD). METHODS: This was a prospective, noncomparative, interventional pil...

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Autores principales: Kohli, Gaurav Mohan, Shenoy, Pratik, Halim, Danish, Nigam, Saurabh, Shetty, Sachin, Talwar, Dinesh, Sen, Alok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9240553/
https://www.ncbi.nlm.nih.gov/pubmed/35326041
http://dx.doi.org/10.4103/ijo.IJO_1788_21
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author Kohli, Gaurav Mohan
Shenoy, Pratik
Halim, Danish
Nigam, Saurabh
Shetty, Sachin
Talwar, Dinesh
Sen, Alok
author_facet Kohli, Gaurav Mohan
Shenoy, Pratik
Halim, Danish
Nigam, Saurabh
Shetty, Sachin
Talwar, Dinesh
Sen, Alok
author_sort Kohli, Gaurav Mohan
collection PubMed
description PURPOSE: To study the safety and efficacy of pre-operative suprachoroidal triamcinolone acetonide (SCTA) for achieving reduction/resolution of serous choroidal detachment (CD) associated with rhegmatogenous retinal detachment (RRD). METHODS: This was a prospective, noncomparative, interventional pilot study. All consecutive patients presenting with RD and coexisting CD underwent transconjunctival injection of SCTA before proceeding with vitrectomy/scleral buckle surgery. Sequential ultrasound B scans were performed for assessing the change in height of the CD. RESULTS: The mean age of the cohort was 53.8 ± 10.8 years (range: 39–72 years). The CD was present in a median of 3 quadrants; the cumulative mean CD height was 5.59 mm (range: 2.02–9.42 mm). Following SCTA, a successful response (>50% reduction) was seen in five eyes by day 3 and in two eyes by day 5. Three eyes failed to respond to SCTA and required surgical drainage before proceeding with vitrectomy. No intraprocedural injection-related complications were noted. A transient rise in the intraocular pressure (30 mmHg) was seen in one eye following vitrectomy and was managed successfully with topical antiglaucoma medications CONCLUSION: Suprachoroidal administration of triamcinolone appears to be a safe and effective technique to achieve CD resolution in eyes with RRD.
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spelling pubmed-92405532022-06-30 Safety and efficacy of suprachoroidal triamcinolone acetonide for the management of serous choroidal detachment prior to rhegmatogenous retinal detachment surgery: A Pilot study Kohli, Gaurav Mohan Shenoy, Pratik Halim, Danish Nigam, Saurabh Shetty, Sachin Talwar, Dinesh Sen, Alok Indian J Ophthalmol Special Focus, Retina, Original Article PURPOSE: To study the safety and efficacy of pre-operative suprachoroidal triamcinolone acetonide (SCTA) for achieving reduction/resolution of serous choroidal detachment (CD) associated with rhegmatogenous retinal detachment (RRD). METHODS: This was a prospective, noncomparative, interventional pilot study. All consecutive patients presenting with RD and coexisting CD underwent transconjunctival injection of SCTA before proceeding with vitrectomy/scleral buckle surgery. Sequential ultrasound B scans were performed for assessing the change in height of the CD. RESULTS: The mean age of the cohort was 53.8 ± 10.8 years (range: 39–72 years). The CD was present in a median of 3 quadrants; the cumulative mean CD height was 5.59 mm (range: 2.02–9.42 mm). Following SCTA, a successful response (>50% reduction) was seen in five eyes by day 3 and in two eyes by day 5. Three eyes failed to respond to SCTA and required surgical drainage before proceeding with vitrectomy. No intraprocedural injection-related complications were noted. A transient rise in the intraocular pressure (30 mmHg) was seen in one eye following vitrectomy and was managed successfully with topical antiglaucoma medications CONCLUSION: Suprachoroidal administration of triamcinolone appears to be a safe and effective technique to achieve CD resolution in eyes with RRD. Wolters Kluwer - Medknow 2022-04 2022-03-22 /pmc/articles/PMC9240553/ /pubmed/35326041 http://dx.doi.org/10.4103/ijo.IJO_1788_21 Text en Copyright: © 2022 Indian Journal of Ophthalmology https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Special Focus, Retina, Original Article
Kohli, Gaurav Mohan
Shenoy, Pratik
Halim, Danish
Nigam, Saurabh
Shetty, Sachin
Talwar, Dinesh
Sen, Alok
Safety and efficacy of suprachoroidal triamcinolone acetonide for the management of serous choroidal detachment prior to rhegmatogenous retinal detachment surgery: A Pilot study
title Safety and efficacy of suprachoroidal triamcinolone acetonide for the management of serous choroidal detachment prior to rhegmatogenous retinal detachment surgery: A Pilot study
title_full Safety and efficacy of suprachoroidal triamcinolone acetonide for the management of serous choroidal detachment prior to rhegmatogenous retinal detachment surgery: A Pilot study
title_fullStr Safety and efficacy of suprachoroidal triamcinolone acetonide for the management of serous choroidal detachment prior to rhegmatogenous retinal detachment surgery: A Pilot study
title_full_unstemmed Safety and efficacy of suprachoroidal triamcinolone acetonide for the management of serous choroidal detachment prior to rhegmatogenous retinal detachment surgery: A Pilot study
title_short Safety and efficacy of suprachoroidal triamcinolone acetonide for the management of serous choroidal detachment prior to rhegmatogenous retinal detachment surgery: A Pilot study
title_sort safety and efficacy of suprachoroidal triamcinolone acetonide for the management of serous choroidal detachment prior to rhegmatogenous retinal detachment surgery: a pilot study
topic Special Focus, Retina, Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9240553/
https://www.ncbi.nlm.nih.gov/pubmed/35326041
http://dx.doi.org/10.4103/ijo.IJO_1788_21
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