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Location-Dependent Human Osteoarthritis Cartilage Response to Realistic Cyclic Loading: Ex-Vivo Analysis on Different Knee Compartments

Objective: Osteoarthritis (OA) is a multifactorial musculoskeletal disorder affecting mostly weight-bearing joints. Chondrocyte response to load is modulated by inflammatory mediators and factors involved in extracellular cartilage matrix (ECM) maintenance, but regulatory mechanisms are not fully cl...

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Detalles Bibliográficos
Autores principales:	Assirelli, Elisa, Caravaggi, Paolo, Mazzotti, Antonio, Ursini, Francesco, Leardini, Alberto, Belvedere, Claudio, Neri, Simona
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Bioengineering and Biotechnology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9240619/ https://www.ncbi.nlm.nih.gov/pubmed/35782520 http://dx.doi.org/10.3389/fbioe.2022.862254

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