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May the 4C's be with you: an overview of complexity-inspired frameworks for analysing resting-state neuroimaging data

Competing and complementary models of resting-state brain dynamics contribute to our phenomenological and mechanistic understanding of whole-brain coordination and communication, and provide potential evidence for differential brain functioning associated with normal and pathological behaviour. Thes...

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Autores principales: Hancock, Fran, Rosas, Fernando E., Mediano, Pedro A. M., Luppi, Andrea I., Cabral, Joana, Dipasquale, Ottavia, Turkheimer, Federico E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9240685/
https://www.ncbi.nlm.nih.gov/pubmed/35765805
http://dx.doi.org/10.1098/rsif.2022.0214
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author Hancock, Fran
Rosas, Fernando E.
Mediano, Pedro A. M.
Luppi, Andrea I.
Cabral, Joana
Dipasquale, Ottavia
Turkheimer, Federico E.
author_facet Hancock, Fran
Rosas, Fernando E.
Mediano, Pedro A. M.
Luppi, Andrea I.
Cabral, Joana
Dipasquale, Ottavia
Turkheimer, Federico E.
author_sort Hancock, Fran
collection PubMed
description Competing and complementary models of resting-state brain dynamics contribute to our phenomenological and mechanistic understanding of whole-brain coordination and communication, and provide potential evidence for differential brain functioning associated with normal and pathological behaviour. These neuroscientific theories stem from the perspectives of physics, engineering, mathematics and psychology and create a complicated landscape of domain-specific terminology and meaning, which, when used outside of that domain, may lead to incorrect assumptions and conclusions within the neuroscience community. Here, we review and clarify the key concepts of connectivity, computation, criticality and coherence—the 4C's—and outline a potential role for metastability as a common denominator across these propositions. We analyse and synthesize whole-brain neuroimaging research, examined through functional magnetic imaging, to demonstrate that complexity science offers a principled and integrated approach to describe, and potentially understand, macroscale spontaneous brain functioning.
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spelling pubmed-92406852022-07-08 May the 4C's be with you: an overview of complexity-inspired frameworks for analysing resting-state neuroimaging data Hancock, Fran Rosas, Fernando E. Mediano, Pedro A. M. Luppi, Andrea I. Cabral, Joana Dipasquale, Ottavia Turkheimer, Federico E. J R Soc Interface Review Articles Competing and complementary models of resting-state brain dynamics contribute to our phenomenological and mechanistic understanding of whole-brain coordination and communication, and provide potential evidence for differential brain functioning associated with normal and pathological behaviour. These neuroscientific theories stem from the perspectives of physics, engineering, mathematics and psychology and create a complicated landscape of domain-specific terminology and meaning, which, when used outside of that domain, may lead to incorrect assumptions and conclusions within the neuroscience community. Here, we review and clarify the key concepts of connectivity, computation, criticality and coherence—the 4C's—and outline a potential role for metastability as a common denominator across these propositions. We analyse and synthesize whole-brain neuroimaging research, examined through functional magnetic imaging, to demonstrate that complexity science offers a principled and integrated approach to describe, and potentially understand, macroscale spontaneous brain functioning. The Royal Society 2022-06-29 /pmc/articles/PMC9240685/ /pubmed/35765805 http://dx.doi.org/10.1098/rsif.2022.0214 Text en © 2022 The Authors. https://creativecommons.org/licenses/by/4.0/Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, provided the original author and source are credited.
spellingShingle Review Articles
Hancock, Fran
Rosas, Fernando E.
Mediano, Pedro A. M.
Luppi, Andrea I.
Cabral, Joana
Dipasquale, Ottavia
Turkheimer, Federico E.
May the 4C's be with you: an overview of complexity-inspired frameworks for analysing resting-state neuroimaging data
title May the 4C's be with you: an overview of complexity-inspired frameworks for analysing resting-state neuroimaging data
title_full May the 4C's be with you: an overview of complexity-inspired frameworks for analysing resting-state neuroimaging data
title_fullStr May the 4C's be with you: an overview of complexity-inspired frameworks for analysing resting-state neuroimaging data
title_full_unstemmed May the 4C's be with you: an overview of complexity-inspired frameworks for analysing resting-state neuroimaging data
title_short May the 4C's be with you: an overview of complexity-inspired frameworks for analysing resting-state neuroimaging data
title_sort may the 4c's be with you: an overview of complexity-inspired frameworks for analysing resting-state neuroimaging data
topic Review Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9240685/
https://www.ncbi.nlm.nih.gov/pubmed/35765805
http://dx.doi.org/10.1098/rsif.2022.0214
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