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Morphine analgesia in male inbred genetic diversity mice recapitulates the among‐individual variance in response to morphine in humans

Morphine is a widely used analgesic, but its use in clinical precision medicine is limited by the variance in response among individuals. Although previous studies have shown that individual differences in morphine can be explained in terms of pharmacodynamics and pharmacokinetics, genetic polymorph...

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Detalles Bibliográficos
Autores principales: Yang, Yin, Guan, Bowen, Wei, Qiang, Wang, Wei, Meng, Aimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9240740/
https://www.ncbi.nlm.nih.gov/pubmed/35656737
http://dx.doi.org/10.1002/ame2.12234