Tumor immune microenvironment of primary prostate cancer with and without germline mutations in homologous recombination repair genes

BACKGROUND: Aberrations in homologous recombination repair (HRR) genes are emerging as important biomarkers for personalized treatment in prostate cancer (PCa). HRR deficiency (HRD) could affect the tumor immune microenvironment (TIME), potentially contributing to differential responses to poly ADP-...

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Detalles Bibliográficos
Autores principales: Trigos, Anna Sofia, Pasam, Anupama, Banks, Patricia, Wallace, Roslyn, Guo, Christina, Keam, Simon, Thorne, Heather, Mitchell, Catherine, Lade, Stephen, Clouston, David, Hakansson, Alexander, Liu, Yang, Blyth, Benjamin, Murphy, Declan, Lawrentschuk, Nathan, Bolton, Damien, Moon, Daniel, Darcy, Phil, Haupt, Ygal, Williams, Scott G, Castro, Elena, Olmos, David, Goode, David, Neeson, Paul, Sandhu, Shahneen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Basic Tumor Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9240881/
https://www.ncbi.nlm.nih.gov/pubmed/35764368
http://dx.doi.org/10.1136/jitc-2021-003744

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