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Hemorrhage Risk Among Patients With Breast Cancer Receiving Concurrent Direct Oral Anticoagulants With Tamoxifen vs Aromatase Inhibitors

IMPORTANCE: Tamoxifen is commonly used as adjuvant therapy in breast cancer and is proposed to interfere with cytochrome P450 enzyme and P-glycoprotein pathways. Concurrent use with direct oral anticoagulants (DOACs) poses the threat of a potentially dangerous drug-drug interaction by leading to an...

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Detalles Bibliográficos
Autores principales:	Wang, Tzu-Fei, Clarke, Anna E., Awan, Arif A., Tanuseputro, Peter, Carrier, Marc, Sood, Manish M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Medical Association 2022
Materias:	Original Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9240900/ https://www.ncbi.nlm.nih.gov/pubmed/35763294 http://dx.doi.org/10.1001/jamanetworkopen.2022.19128

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