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Enhanced Microvasculature Formation and Patterning in iPSC–Derived Kidney Organoids Cultured in Physiological Hypoxia

Stem cell–derived kidney organoids have been shown to self-organize from induced pluripotent stem cells into most important renal structures. However, the structures remain immature in culture and contain endothelial networks with low connectivity and limited organoid invasion. Furthermore, the neph...

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Detalles Bibliográficos
Autores principales:	Schumacher, Anika, Roumans, Nadia, Rademakers, Timo, Joris, Virginie, Eischen-Loges, Maria José, van Griensven, Martijn, LaPointe, Vanessa L.S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Bioengineering and Biotechnology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9240933/ https://www.ncbi.nlm.nih.gov/pubmed/35782512 http://dx.doi.org/10.3389/fbioe.2022.860138

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