Cargando…

Synthesis, crystal structure and in silico studies of novel 2,4-dimethoxy-tetrahydropyrimido[4,5-b]quinolin-6(7H)-ones

Herein, acetic acid mediated multicomponent synthesis of novel 2,4-dimethoxy-tetrahydropyrimido[4,5-b]quinolin-6(7H)-one (2,4-dimethoxy-THPQs) was reported. Single-crystal XRD analysis of four newly developed crystals of 2,4-dimethoxy-THPQs and their DFT study were also reported. The structure of al...

Descripción completa

Detalles Bibliográficos
Autores principales:	Patel, Subham G., Vala, Ruturajsinh M., Patel, Paras J., Upadhyay, Dipti B., Ramkumar, V., Gardas, Ramesh L., Patel, Hitendra M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2022
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9240959/ https://www.ncbi.nlm.nih.gov/pubmed/35873341 http://dx.doi.org/10.1039/d2ra02694e

Ejemplares similares

Microwave-assisted multicomponent synthesis of antiproliferative 2,4-dimethoxy-tetrahydropyrimido[4,5-b]quinolin-6(7H)-ones
por: Patel, Subham G., et al.
Publicado: (2022)

Catalyst-Free, Room-Temperature Accessible Regioselective Synthesis of Spiroquinolines and Their Antioxidant Study
por: Patel, Paras J., et al.
Publicado: (2022)

An efficient, catalyst-free and aqueous ethanol-mediated synthesis of 5-((2-aminothiazol-5-yl)(phenyl)methyl)-6-hydroxypyrimidine-2,4(1H,3H)-dione derivatives and their antioxidant activity
por: Patel, Paras J., et al.
Publicado: (2023)

Importance of Hybrid Catalysts toward the Synthesis of 5H-Pyrano[2,3-d]pyrimidine-2-ones/2,4-diones (Thiones)
por: Parmar, Mehul P., et al.
Publicado: (2023)

Pyridine-2-carboxylic acid as an effectual catalyst for rapid multi-component synthesis of pyrazolo[3,4-b]quinolinones
por: Sharma, Mayank G., et al.
Publicado: (2020)

6,7-Dimethoxy-2,4-diphenylquinoline
por: Prabhuswamy, M., et al.
Publicado: (2014)

One-pot two-step catalytic synthesis of 6-amino-2-pyridone-3,5-dicarbonitriles enabling anti-cancer bioactivity
por: Nicely, Lynden G., et al.
Publicado: (2022)

Versatile Synthetic Platform for 1,2,3-Triazole Chemistry
por: Vala, Disha P., et al.
Publicado: (2022)

A novel substrate directed multicomponent reaction for the syntheses of tetrahydro-spiro[pyrazolo[4,3-f]quinoline]-8,5′-pyrimidines and tetrahydro-pyrazolo[4,3-f]pyrimido[4,5-b]quinolines via selective multiple C–C bond formation under metal-free conditions
por: Patel, Divyang M., et al.
Publicado: (2020)

Impact of an aryl bulky group on a one-pot reaction of aldehyde with malononitrile and N-substituted 2-cyanoacetamide
por: Vala, Ruturajsinh M., et al.
Publicado: (2019)

Synthesis of N-(4-chlorophenyl) substituted pyrano[2,3-c]pyrazoles enabling PKBβ/AKT2 inhibitory and in vitro anti-glioma activity
por: Vala, Ruturajsinh M., et al.
Publicado: (2022)

2,4-Dimethoxybenzaldehyde azine
por: Islam, M. A. A. A. A., et al.
Publicado: (2009)

2-Bromo-5,7-dimethoxy-4-phenylquinoline
por: Gopal, Veshal, et al.
Publicado: (2009)

4-Phenyl-1,2,3,4-tetrahydropyrimido[1,2-a]benzimidazol-2-one
por: Li, Gong-Chun, et al.
Publicado: (2008)

1-Bromo-2-chloro-4,5-dimethoxybenzene
por: Song, Yang, et al.
Publicado: (2010)

2,4-Dichloroquinoline
por: Kimmel, Roman, et al.
Publicado: (2010)

3-(2-Bromo-4,5-dimethoxyphenyl)propiononitrile
por: Liu, Yan-Ping, et al.
Publicado: (2008)

5,8-Dimethoxy-2-phenyl-1,4-dihydroquinoline-3-carbonitrile
por: Ladraa, Souheila, et al.
Publicado: (2010)

3-(2-Chloro-3-hydroxy-4-methoxyphenyl)-1-(4,5-dimethoxy-2-methylphenyl)prop-2-en-1-one
por: Patel, U. H., et al.
Publicado: (2012)

(E)-4-Bromo-N-(2,4-dimethoxybenzylidene)aniline
por: Khalaji, Aliakbar D., et al.
Publicado: (2009)

Syrbactin-class dual constitutive- and immuno-proteasome inhibitor TIR-199 impedes myeloma-mediated bone degeneration in vivo
por: Tandon, Vasudha, et al.
Publicado: (2022)

1-Bromo-2,3,6-trichloro-4,5-dimethoxybenzene
por: Song, Yang, et al.
Publicado: (2010)

1,2-Bis(bromomethyl)-4,5-dimethoxybenzene
por: Zhou, Feng-yan
Publicado: (2009)

Molecular Insights of 1,2,3,4-tetrahydropyrimido[1,2-a]benzimidazole as CRF-1 Receptor Antagonists: Combined QSAR, Glide Docking, Molecular Dynamics, and In-silico ADME Studies
por: Kumar, Sunil, et al.
Publicado: (2021)

6-Methyl-2,4-diphenylquinoline
por: Huo, Xing, et al.
Publicado: (2008)

2,4-Dichloro-6-methoxyquinoline
por: Subashini, R., et al.
Publicado: (2009)

9-Chloro-2,4-dimethoxyacridinium trifluoromethanesulfonate
por: Zadykowicz, Beata, et al.
Publicado: (2009)

Microwave produced 8-methyl-1,2,4,8-tetraazaspiro[4.5]dec-2-en-3-amine derivatives: their in vitro and in silico analysis
por: Patel, Parth P., et al.
Publicado: (2023)

2,4-Dichloro-7,8-dimethylquinoline
por: Subashini, R., et al.
Publicado: (2010)

N′-(2,3-Dimethoxybenzylidene)-2,4-dihydroxybenzohydrazide
por: Han, You-Yue, et al.
Publicado: (2010)

(2,4-Dimethoxybenzylidene)-2-hydroxybenzohydrazide ethanol solvate
por: Yehye, Wagee A., et al.
Publicado: (2008)

2,4-Dibromo-1,3-dimethoxy-5-methylbenzene
por: Pawar, Sunayna, et al.
Publicado: (2012)

4-Hydrazinyl-1-isobutyl-1H-imidazo[4,5-c]quinoline
por: Loh, Wan-Sin, et al.
Publicado: (2011)

Packing polymorphism in the crystal structure of 4,5-dimethoxy-2-nitrobenzyl acetate
por: Kasuga, Noriko Chikaraishi, et al.
Publicado: (2015)

Ethyl 2-(2,6-difluorobenzyloxy)-4-(4,6-dimethoxypyrimidin-2-yl)quinoline-3-carboxylate
por: Li, Yuan-xiang
Publicado: (2009)

N′-(2,4-Dimethoxybenzylidene)-3,4,5-trihydroxybenzohydrazide ethanol solvate
por: Alhadi, Abeer A., et al.
Publicado: (2009)

(E)-N′-(3,4-Dimethoxybenzylidene)-2,4-dihydroxybenzohydrazide methanol solvate
por: Zhang, Qiao-Ling, et al.
Publicado: (2009)

(E)-N′-(2,5-Dimethoxybenzylidene)-2,4-dihydroxybenzohydrazide
por: Wei, Jing-Yuan, et al.
Publicado: (2010)

1-Isobutyl-4-methoxy-1H-imidazo[4,5-c]quinoline
por: Fun, Hoong-Kun, et al.
Publicado: (2011)

2-(4,5-Dihydro-1,3-oxazol-2-yl)quinoline
por: Machado, Pablo, et al.
Publicado: (2007)

Cannot write session to /tmp/vufind_sessions/sess_4qoj1kag82f9jhoppr36vqm13h