Guanine nucleotide exchange factor DOCK11-binding peptide fused with a single chain antibody inhibits hepatitis B virus infection and replication

Hepatitis B virus (HBV) infection is a major global health problem with no established cure. Dedicator of cytokinesis 11 (DOCK11), known as a guanine nucleotide exchange factor (GEF) for Cdc42, is reported to be essential for the maintenance of HBV. However, potential therapeutic strategies targetin...

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Detalles Bibliográficos
Autores principales: Ide, Mayuko, Tabata, Noriko, Yonemura, Yuko, Shirasaki, Takayoshi, Murai, Kazuhisa, Wang, Ying, Ishida, Atsuya, Okada, Hikari, Honda, Masao, Kaneko, Shuichi, Doi, Nobuhide, Ito, Satoru, Yanagawa, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241042/
https://www.ncbi.nlm.nih.gov/pubmed/35660020
http://dx.doi.org/10.1016/j.jbc.2022.102097

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